VX 702
VX 702
- CAS:
- 745833-23-2
- MF:
- C19H12F4N4O2
- MW:
- 404.32
Suppliers by country/region
Company Type
Properties
- Boiling point:
- 555.2±60.0 °C(Predicted)
- Density
- 1.503
- storage temp.
- -20°C
- solubility
- Soluble in DMSO (up to 40 mg/ml) or in Ethanol (up to 2 mg/ml)
- pka
- 10.65±0.50(Predicted)
- form
- solid
- color
- White
- Stability:
- Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
Safety Information
- Symbol(GHS)
GHS07
- Signal word
- Warning
- Hazard statements
- H315-H319
- Precautionary statements
- P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313
- HS Code
- 2933399990
Use
VX-702 is a third generation inhibitor of p38 mitogen-activated protein (MAP) kinases, binding to both p38α and p38β (Kd = 3.7 and 17 nM, respectively) in an ATP-competitive fashion. It inhibits IL-6, IL-1β, and TNF-α production in LPS-primed blood with IC50 values of 59, 122, and 99 ng/ml, respectively. VX-702, at 1 μM, inhibits activation of p38 in platelets by thrombin, U-46619 , or collagen but does not block platelet aggregation in response to collagen. Although orally active, VX-702 provides only transient suppression of biomarkers of inflammation in ongoing rheumatoid arthritis.[Cayman Chemical]
1 India supplier list of "VX 702"
- Product Name:VX-702 >95%
- Products Intro:Brand：Glrinnovations | OriginalID：GLR19.089132
- Company Type: Trader
- Country/Region: New Delhi,INDIA
- Product Name:VX-702
- Products Intro:Brand:clearsynth | Product Number:CS-T-46561
- Company Type: Trader
- Country/Region: Hyderabad,INDIA
- Product Name:VX-702
- Products Intro:Brand:ajchemicals | Product Number:JDH-38470 | Purity:98+%
- Company Type: Trader
- Country/Region: New Delhi,INDIA
- Product Name:VX-702
- Products Intro:Brand:tcichemicals | Product Number:V0147
- Company Type: Reagent
- Country/Region: New Delhi,INDIA
- Product Name:VX702
- Products Intro:Purity: 98% | Package: 10MG;50MG;100MG,1G,5G,10G.100G
- Company Type: Reagent
- Country/Region: CHINA
- Product Name:VX 702
- Products Intro:Purity: 0.98 | Package: 1kg，2kg，5kg，10kg，25kg
- Company Type: Trader
- Country/Region: CHINA
- Main Products: 2,7-ADA,2,4,6-Trichloroaniline,TRIMETHYLOXONIUM TETRAFLUOROBORATE,Zinc sulfide,5-HEXEN-1-OL
- Product Name:(479543-46-9) vx 702
- Products Intro:Purity: 99% | Package: 1kg
- Company Type: Trader
- Country/Region: CHINA
- Product Name:VX 702
- Products Intro:Purity: 99.9% | Package: 25kgs/Drum;200kgs/Drum | CustNote: FDA GMP CEP Approved Manufacturer
- Company Type: Trader
- Country/Region: CHINA
- Product Name:VX-702 VX702
- Products Intro:Purity: 99% | Package: 5KG;1KG
- Company Type: Trader
- Country/Region: CHINA
- Main Products: sarms