AGI6780
AGI6780
- CAS:
- 1432660-47-3
- MF:
- C21H18F3N3O3S2
- MW:
- 481.51
Suppliers by country/region
Company Type
Properties
- Density
- 1.52±0.1 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- ≥22.25 mg/mL in DMSO; insoluble in H2O; ≥100.8 mg/mL in EtOH
- form
- solid
- pka
- 11.78±0.20(Predicted)
- color
- White to off-white
Safety Information
- HS Code
- 2935909099
Use
AGI-6780 potently reduce (R)-2-hydroxyglutarate (2HG) levels in cell lines ectopically overexpressing IDH2/R140Q with EC50 of 20 nM, with excellent selectivity against other dehydrogenases. AGI-6780 reverses the IDH2/R140Q-induced differentiation block in TF-1 cells, and induces blast differentiation in primary human IDH2/R140Q AML patient samples.
0 India supplier list of "AGI6780"
- Product Name:IDH2Inhibitor,R140QSomaticMutant-Specific,AGI-6780-CAS1432660-47-3-Calbiochem
- Products Intro:Brand:sigma aldrich | Product Number:5.09880 | Purity:Acell-permeableinhibitorofisocitratedehydrogenase2R140Qmutant-containingdimers.H
- Company Type: Trader
- Country/Region: Bangalore,INDIA
- Product Name:AGI-6780
- Products Intro:Brand:ajchemicals | Product Number:JDH-26180 | Purity:98+%
- Company Type: Trader
- Country/Region: New Delhi,INDIA
- Product Name:AGI-6780
- Products Intro:Purity: 98% | Package: 10MG;50MG;100MG,1G,5G,10G.100G
- Company Type: Reagent
- Country/Region: CHINA
- Product Name:AGI6780
- Products Intro:Purity: 0.98 | Package: 1kg，2kg，5kg，10kg，25kg
- Company Type: Trader
- Country/Region: CHINA
- Main Products: 2,7-ADA,2,4,6-Trichloroaniline,TRIMETHYLOXONIUM TETRAFLUOROBORATE,Zinc sulfide,5-HEXEN-1-OL
- Product Name:AGI-6780；AGI6780;AGI 6780
- Products Intro:Purity: 98.19% | Package: 1 mL * 10mM (in DMSO)；10 mg；100 mg；2 mg；25 mg；5 mg；50 mg | CustNote: REAGENT;FOR LABORATORY USE ONLY
- Company Type: Trader
- Country/Region: UNITED STATES
- Main Products: Compound Libraries,Noval Small Molecucles,Nature Compounds,Inhibitory Antibodies,Life science Kits
- Product Name:AGI6780
- Products Intro:Purity: 99.9% | Package: 25kgs/Drum;200kgs/Drum | CustNote: FDA GMP CEP Approved Manufacturer
- Company Type: Trader
- Country/Region: CHINA
- Product Name:AGI6780
- Products Intro:Package: 1KG;25kg;200kg;1000kg Elin | CustNote: g-kg-tons,free sample is available.Bottle/drum/IBC.Advantage products,new batches,regular stock, ready for shipment.
- Company Type: Trader
- Country/Region: CHINA
- Main Products: Chemical raw materials,Organic raw materials,Petrochemicals,Chemical reagents,Intermediates
- Product Name:AGI-6780
- Products Intro:Purity: >=98% | Package: $88.9/5mg;$147.9/10mg;$494.9/50mg;Bulk package | CustNote: 98%
- Company Type: Trader
- Country/Region: UNITED STATES
- Main Products: Chemicals and BioChemicals,Materials Science,ligands acting on targets,Proteins,Antibodies