ANA12
ANA12
- CAS:
- 219766-25-3
- MF:
- C22H21N3O3S
- MW:
- 407.49
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Properties
- Boiling point:
- 639.2±55.0 °C(Predicted)
- Density
- 1.36±0.1 g/cm3(Predicted)
- storage temp.
- 2-8°C
- solubility
- DMSO: ≥5mg/mL at 60°C
- form
- powder
- pka
- 12.09±0.70(Predicted)
- color
- white to beige
- Stability:
- Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 2 months.
Safety Information
- Symbol(GHS)
GHS07
- Signal word
- Warning
- Hazard statements
- H302
- Precautionary statements
- P264-P270-P301+P312-P501
- Hazard Codes
- Xn
- Risk Statements
- 22
- WGK Germany
- 3
Use
ANA-12 binds directly and selectively to TrkB and inhibits processes downstream of TrkB without altering TrkA and TrkC functions. In nnr5 PC12-TrkB cells, ANA-12 prevents brain-derived neurotrophic factor (BDNF)-induced neurite outgrowth at concentrations as low as 10 nM. In DRG neurons, ANA-12 eliminates the effect of BDNF on increasing inward current.
1 India supplier list of "ANA12"
![](/images/pro-3.jpg)
- Product Name:TrkBAntagonist,ANA-12-CAS219766-25-3-Calbiochem
- Products Intro:Brand:sigma aldrich | Product Number:5.06304
- Company Type: Trader
- Country/Region: INDIA