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Budesonide

Budesonide

CAS:
51333-22-3
MF:
C25H34O6
MW:
430.53

Properties

Melting point:
221-232°C (dec.)
alpha 
D25 +98.9° (c = 0.28 in methylene chloride)
Boiling point:
464.79°C (rough estimate)
Density 
1.1046 (rough estimate)
refractive index 
1.4593 (estimate)
storage temp. 
Store at RT
solubility 
Practically insoluble in water, freely soluble in methylene chloride, sparingly soluble in ethanol (96 per cent).
form 
powder
pka
12.87±0.10(Predicted)
color 
White to Off-White
Water Solubility 
21.53mg/L(temperature not stated)
Merck 
14,1468
BCS Class
2
InChIKey
VOVIALXJUBGFJZ-KWVAZRHASA-N

Safety Information

Symbol(GHS) 
GHS hazard pictogramsGHS hazard pictograms
GHS08,GHS07
Signal word 
Danger
Hazard statements 
H361-H332-H317-H334-H312
Precautionary statements 
P261-P272-P280-P302+P352-P333+P313-P321-P363-P501-P201-P202-P281-P308+P313-P405-P501-P261-P271-P304+P340-P312-P280-P302+P352-P312-P322-P363-P501-P261-P285-P304+P341-P342+P311-P501
Hazard Codes 
Xn
Risk Statements 
40-36/37/38-20/21/22
Safety Statements 
22-36-26
WGK Germany 
3
RTECS 
TU3723000
HS Code 
29372900
Toxicity
LD50 oral in rat: > 3200mg/kg

Use

Budesonide, 16α,17-[butylidenebis-(oxy)]-11β,21-dihydroxypregna-1,4-diene-3, 20-dione (Entocort), in oral capsules is used to treat Crohn disease. Theaffinity for the GC is approximately 200-fold greater than thatof hydrocortisone and 15-fold greater than that of prednisolone.Budesonide is a mixture of epimers, with the 22Rform having twice the affinity for the GR of the S epimer.This GC is metabolized by CYP3A4, and its levels can be increasedin the presence of potent CYP3A4 inhibitors.Budesonide is also used in an inhaled formulation for thetreatment of asthma.

100 India supplier list of "Budesonide"

  • Product Name:Budesonide
  • Company Type: Trader
  • Country/Region: New Delhi,INDIA
Coral Drugs Pvt Ltd
  • Product Name:Budesonide
  • Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
  • Company Type: Manufacturer
  • Country/Region: New Delhi,INDIA
Moleculochem
  • Product Name:Budesonide
  • Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
  • Company Type: Reagent
  • Country/Region: New Delhi,INDIA
Avik Pharmaceutical Limited
  • Product Name:Budesonide
  • Products Intro:Purity: 99% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
  • Company Type: Manufacturer
  • Country/Region: Maharashtra,INDIA
Micro Orgo Chem
  • Product Name:BUDESONIDE
  • Products Intro:Purity: 99% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
  • Company Type: Manufacturer
  • Country/Region: Mumbai,INDIA
Gonane Pharma
  • Product Name:Budesonide
  • Products Intro:Purity: 99% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
  • Company Type: Trader
  • Country/Region: NaviMumbai,INDIA
Rivashaa Agrotech Biopharma Pvt. Ltd.
  • Product Name:Budesonide
  • Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg
  • Company Type: Reagent
  • Country/Region: Gujarat,INDIA
Ralington Pharma
  • Product Name:Budesonide
  • Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
  • Company Type: Reagent
  • Country/Region: Gujarat,INDIA
Swati Spentose Pvt Ltd
  • Product Name:Budesonide
  • Products Intro:Purity: 99% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
  • Company Type: Manufacturer
  • Country/Region: Maharashtra,INDIA
Aarti Industries Limited (AIL)
  • Product Name:Budesonide
  • Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg
  • Company Type: Manufacturer
  • Country/Region: Maharashtra,INDIA

Budesonide Related Search:

LevonorgestrelLevosulpirideLevofloxacinCalcium levofolinateDi-Norbudesonide (Mixture of DiastereoMers)21-Dehydro Budesonide14,15-Dehydro Budesonide9α-BroMobudesonide16α,17-[(1RS)-Butylidenebis(oxy)]-11β-hydroxy-17-(hydroxyMethyl)-D-hoMoandrosta-1,4-diene-3,17a-dione (Mixture of DiastereoMers)BetamethasoneDesonide1,4-DioxaneSelenium dioxide DIOXOPROMETHAZINE HCL(r)-budesonideLevodropropizineCiclesonide6-BETA-HYDROXY BUDESONIDE
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