Clindamycin phosphate manufacturers and suppliers in india

Clindamycin phosphate

Properties

Melting point:: 114 °C

Boiling point:: 159°C

Density: 1.41±0.1 g/cm3(Predicted)

refractive index: 122 ° (C=1, H2O)

storage temp.: Sealed in dry,2-8°C

solubility: DMSO: soluble224mg/mL at 25°C

form: solid

pka: pKa 0.964±0.06 (H2O t=21) (Uncertain);6.06 ±0.06 (I=0.008)(H2O t=21) (Uncertain)

color: White

Water Solubility: Freely soluble in water

Merck: 14,2356

Stability:: Stable, but store cool. Incompatible with strong oxidizing agents, calcium gluconate, barbiturates, magnesium sulfate, phenytoin, B group sodium vitamins.

InChIKey: UFUVLHLTWXBHGZ-YFBDLMQENA-N

SMILES: [C@]([H])([C@]1([H])[C@@H]([C@H](O)[C@@H](OP(O)(O)=O)[C@@H](SC)O1)O)([C@@H](Cl)C)NC([C@H]1N(C[C@H](CCC)C1)C)=O |&1:0,2,4,5,7,13,18,23,26,r|

Safety Information

Symbol(GHS): GHS07

Signal word: Warning

Hazard statements: H302-H317-H319-H362

Precautionary statements: P260-P263-P280-P301+P312-P302+P352-P308+P313

Hazard Codes: Xn,Xi

Risk Statements: 22-36/37/38

Safety Statements: 36-26

WGK Germany: 3

RTECS: GF2625000

HS Code: 29419000

Use

Clindamycin phosphate (Cleocin Phosphate) is the 2-phosphateester of clindamycin. It exists as a zwitterionic structurethat is very soluble in water. It is intended for parenteral(intravenous or intramuscular) administration for the treatmentof serious infections and instances when oral administrationis not feasible. Solutions of clindamycin phosphateare stable at room temperature for 16 days and for up to 32days when refrigerated.