Doxycycline
Doxycycline
- CAS:
- 564-25-0
- MF:
- C22H24N2O8
- MW:
- 444.43
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Properties
- Melting point:
- 206-209°C (dec.)
- Boiling point:
- 554.44°C (rough estimate)
- Density
- 1.3809 (rough estimate)
- refractive index
- 1.6500 (estimate)
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- solubility
- DMSO : 125 mg/mL (281.26 mM; Need ultrasonic)
- pka
- pKa 3.5 (Uncertain);7.7 (Uncertain);9.5 (Uncertain)
- form
- Solid
- color
- Light yellow to brown
- Water Solubility
- 0.63g/L(25 ºC)
- BCS Class
- 3,1
- InChIKey
- JBIWCJUYHHGXTC-AKNGSSGZSA-N
- SMILES
- C1(=O)[C@]2(O)[C@@]([H])([C@@H](O)[C@@]3([H])C(=C2O)C(=O)C2=C(C=CC=C2O)[C@@H]3C)[C@H](N(C)C)C(O)=C1C(N)=O
Safety Information
- Hazard statements
- H302-H315-H312-H319-H335-H332
Use
Doxycycline is a semi-synthetic tetracycline prepared by hydrogenolysis of oxytetracycline to remove the 6-hydroxy group. Although the synthesis was reported in 1958, it was not released for use until 1967. Doxycycline, together with minocycline, is regarded as a ‘third generation’ tetracycline largely replacing the analogues and pro-drugs produced in the early 1960s for mainstream antibiotic applications. Like all tetracyclines, doxycycline shows broad spectrum antibacterial and antiprotozoan activity and acts by binding to the 30S and 50S ribosomal subunits, blocking protein synthesis. Doxycycline has been extensively cited in the literature with over 10,000 references.
18 India supplier list of "Doxycycline"
- Product Name:Doxycycline
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Manufacturer
- Country/Region: Telangana,INDIA
- Product Name:Doxycycline
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Reagent
- Country/Region: Gujarat,INDIA
- Product Name:Doxycycline Monohydrate
- Products Intro:Purity: 98% | Package: 25mg; 50mg; 100mg; Customised
- Company Type: Trader
- Country/Region: Punjab,INDIA
- Product Name:Doxycycline
- Products Intro:Purity: 99% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Manufacturer
- Country/Region: AndhraPradesh,INDIA
- Product Name:Doxycycline
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Reagent
- Country/Region: Himachal Pradesh,INDIA
- Product Name:Doxycycline
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Reagent
- Country/Region: Tamil Nadu,INDIA
- Product Name:Doxycycline
- Products Intro:Purity: 99% | Package: 1kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Manufacturer
- Country/Region: Kerela,INDIA
- Product Name:Doxycycline 95.00%
- Products Intro:Brand：Glrinnovations | OriginalID：GLR19.070352
- Company Type: Trader
- Country/Region: New Delhi,INDIA
- Product Name:Doxycycline
- Company Type: Reagent
- Country/Region: Hyderabad,INDIA
- Product Name:Doxycycline
- Products Intro:Brand:synzeal | Product Number:192984911
- Company Type: Trader
- Country/Region: Gujarat,INDIA