Famotidine
Famotidine
- CAS:
- 76824-35-6
- MF:
- C8H15N7O2S3
- MW:
- 337.45
Suppliers by country/region
- India(159)
- China(227)
- United States(63)
- Canada(10)
- United Kingdom(19)
- Russia(1)
- Germany(8)
- Europe(3)
- France(4)
- Switzerland(3)
- Japan(4)
- Philippines(1)
- South Korea(3)
- Brazil(2)
- Spain(6)
- Slovenia(1)
- Poland(3)
- Austria(2)
- Hungary(2)
- The Netherlands(2)
- Uruguay(1)
- Nigeria(1)
- Jordan(1)
- Nepal(1)
- Malaysia(1)
- Indonesia(1)
- United Arab Emirates(1)
Company Type
Properties
- Melting point:
- 163-164°C
- Boiling point:
- 562.7±60.0 °C(Predicted)
- Density
- 1.5111 (rough estimate)
- refractive index
- 1.7400 (estimate)
- storage temp.
- 2-8°C
- solubility
- Very slightly soluble in water, freely soluble in glacial acetic acid, very slightly soluble in anhydrous ethanol, practically insoluble in ethyl acetate. It dissolves in dilute mineral acids
- pka
- pKa 6.76(H2O t=23.0) (Uncertain)
- form
- Solid
- color
- White to Off-White
- Water Solubility
- 1.1 mg/mL
- BCS Class
- 3
- Stability:
- Light Sensitive
- InChI
- InChI=1S/C8H15N7O2S3/c9-6(15-20(12,16)17)1-2-18-3-5-4-19-8(13-5)14-7(10)11/h4H,1-3H2,(H2,9,15)(H2,12,16,17)(H4,10,11,13,14)
- InChIKey
- XUFQPHANEAPEMJ-UHFFFAOYSA-N
- SMILES
- C(NS(N)(=O)=O)(=N)CCSCC1=CSC(NC(N)=N)=N1
Safety Information
- Symbol(GHS)
GHS07
- Signal word
- Warning
- Hazard statements
- H303
- Precautionary statements
- P270-P301+P312-P403-P501c
- Hazard Codes
- T
- Risk Statements
- 20/21/22-45-61
- Safety Statements
- 22-24/25-53-45-36/37/39
- WGK Germany
- 2
- RTECS
- UA2300000
- HS Code
- 29341000
- Toxicity
- LD50 i.v. in mice: 244.4 mg/kg (Yasufumi)
Use
Famotidine is a competitive histamine H2-receptor antagonist, and the main pharmacodynamic effect of famotidine is to cause the inhibition of gastric secretion. Famotidine on decomposition releases toxic products such as carbon oxides (CO, CO2), nitrogen oxides (NO, NO2), and sulphur oxides (SO2, SO3). Famotidine is a medication that is available both in prescription and over-the-counter forms. It is used to treat conditions related to the oesophagus, stomach, and intestines. Some specific famotidine is used for the treatment of duodenal ulcers, gastric ulcers (stomach ulcers), gastroesophageal reflux disease (GERD), and pathological hypersecretory conditions that occur when stomach acid is secreted/ produced in very large quantities, an abnormal health condition called ‘Zollinger-Ellison syndrome’.
159 India supplier list of "Famotidine"
- Product Name:Famotidine
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg
- Company Type: Manufacturer
- Country/Region: Mumbai,INDIA
- Product Name:Famotidine
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg And 1MT
- Company Type: Manufacturer
- Country/Region: Gujarat,INDIA
- Product Name:Famotidine
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Manufacturer
- Country/Region: Telangana,INDIA
- Product Name:Famotidine
- Products Intro:Purity: 99% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Reagent
- Country/Region: Maharashtra,INDIA
- Product Name:Famotidine
- Products Intro:Purity: 99% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Manufacturer
- Country/Region: Uttar Pradesh,INDIA
- Product Name:Famotidine
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Reagent
- Country/Region: Bangalore,INDIA
- Product Name:Famotidine
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Manufacturer
- Country/Region: Telangana,INDIA
- Product Name:Famotidine
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Reagent
- Country/Region: Maharashtra,INDIA
- Product Name:Famotidine
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg
- Company Type: Reagent
- Country/Region: Gujarat,INDIA
- Product Name:Famotidine
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Trader
- Country/Region: Gujarat,INDIA