Ibudilast
Ibudilast
- CAS:
- 50847-11-5
- MF:
- C14H18N2O
- MW:
- 230.31
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Company Type
Properties
- Melting point:
- 53-54°C
- Boiling point:
- 175°C/7.5mmHg(lit.)
- Density
- 1.09
- refractive index
- 1.5500 (estimate)
- storage temp.
- Sealed in dry,2-8°C
- solubility
- DMSO: 28 mg/mL, soluble
- form
- solid
- pka
- 1.22±0.30(Predicted)
- color
- white
- Merck
- 14,4879
- Stability:
- Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
- InChI
- InChI=1S/C14H18N2O/c1-9(2)13-12(14(17)10(3)4)11-7-5-6-8-16(11)15-13/h5-10H,1-4H3
- InChIKey
- ZJVFLBOZORBYFE-UHFFFAOYSA-N
- SMILES
- C(C1=C2N(N=C1C(C)C)C=CC=C2)(=O)C(C)C
Safety Information
- Symbol(GHS)
GHS07
- Signal word
- Warning
- Hazard statements
- H302-H315-H319-H335
- Precautionary statements
- P261-P264-P270-P301+P312-P302+P352-P305+P351+P338
- Hazard Codes
- Xn
- Risk Statements
- 22-36/37/38
- Safety Statements
- 26-36
- WGK Germany
- 3
- RTECS
- UR0711200
- HS Code
- 2933.99.8290
- Toxicity
- LD50 i.v. in mice: 260 mg/kg (Irikura, 1973)
Use
Ibudilast is a leukomene antagonist and phosphodiesterase inhibitor useful in the treatment of bronchial asthma. It antagonizes leukotriene D4-induced contractions of guinea pig ileum and tracheal muscles in virro, and inhibits eosinophil accumulation in vivo.
5 India supplier list of "Ibudilast"
- Product Name:Ibudilast
- Products Intro:Brand:sigma aldrich | Product Number:I0157 | Purity:≥99%(HPLC),solid
- Company Type: Trader
- Country/Region: Bangalore,INDIA
- Product Name:Ibudilast 98.00%
- Products Intro:Brand：Glrinnovations | OriginalID：GLR19.037373
- Company Type: Trader
- Country/Region: New Delhi,INDIA
- Product Name:Ibudilast
- Products Intro:Brand:clearsynth | Product Number:CS-O-11666
- Company Type: Trader
- Country/Region: Hyderabad,INDIA
- Product Name:Ibudilast
- Company Type: Reagent
- Country/Region: Haryana,INDIA
- Product Name:Ibudilast
- Products Intro:Brand:tcichemicals | Product Number:I0740
- Company Type: Reagent
- Country/Region: New Delhi,INDIA
- Product Name:Ibudilast
- Company Type: Reagent
- Country/Region: Maharashtra,INDIA
- Product Name:1-(2-Isopropylpyrazolo[1,5-a]pyridin-3-yl)-2-methylpropan-1-one
- Products Intro:Brand:chemsworth | Product Number:997670822 | Purity:~97%
- Company Type: Trader
- Country/Region: New Delhi,INDIA
- Product Name:Ibudilast
- Products Intro:Brand:pharmaffiliates | Product Number:PA090980000
- Company Type: Trader
- Country/Region: Haryana,INDIA
- Product Name:Ibudilast
- Company Type: Reagent
- Country/Region: Maharashtra,INDIA
- Product Name:Ibudilast
- Company Type: Reagent
- Country/Region: Mumbai,INDIA