Julolidine manufacturers and suppliers in india

Julolidine

Properties

Melting point:: 34-36 °C(lit.)

Boiling point:: 170-173°C 31mm

Density: 1.0030

refractive index: 1.5680

Flash point:: >230 °F

storage temp.: 2-8°C

solubility: Chloroform (Slightly), Ethyl Acetate (Slightly)

form: Liquid After Melting

pka: 6.54±0.20(Predicted)

color: Clear yellow to orange-brown

Water Solubility: Soluble in toluene. Insoluble in water.

Sensitive: Air Sensitive

BRN: 139925

InChIKey: DZFWNZJKBJOGFQ-UHFFFAOYSA-N

Safety Information

Symbol(GHS): GHS07

Signal word: Warning

Hazard statements: H315-H319-H335

Precautionary statements: P261-P305+P351+P338

Risk Statements: 52/53

Safety Statements: 24/25-61

WGK Germany: 3

TSCA: Yes

HS Code: 29339900

Use

Purify julolidine by dissolving it in dilute HCl, steam is bubbled through the solution and the residual acidic solution is basified with 10N NaOH, extracted with Et2O, washed with H2O, dried (NaOH pellets), filtered, evaporated and distilled in vacuo. The distillate crystallises on cooling (m 39-40o). It develops a red colour on standing in contact with air for several days. The colour can be removed by distilling or dissolving in 2-3 parts of hexane, adding charcoal, filtering and cooling in an Me2CO/Dry-ice bath when julolidine crystallises out (85-90% yield m 39-40o). The hydrobromide [83646-41-7] has m 218o (239-242o), the picrate has m 174o(165o) and the methiodide crystallises from MeOH, with m 186o [Glass & Weisberger Org Synth Coll Vol III 504 1955, Smith & Yu J Org Chem 17 1285 1952, Beilstein 20 H 332, 20 I 133, 20 II 214, 20 III/IV 3281.] Highly TOXIC.