LEE011
LEE011
- CAS:
- 1256963-02-6
- MF:
- C22H29ClN8
- MW:
- 440.97
Suppliers by country/region
Company Type
Properties
- Melting point:
- >180°C (dec.)
- Boiling point:
- 679.3±65.0 °C(Predicted)
- Density
- 1.31±0.1 g/cm3(Predicted)
- storage temp.
- -20°C Freezer
- solubility
- DMSO (Slightly), Methanol (Slightly)
- pka
- 7.57±0.50(Predicted)
- form
- Solid
- color
- Beige
Safety Information
Use
LEE011 (also known as ribociclib) is a CDK4/6 inhibitor. It has been recently approved by FDA (brand name: Kisqali) to be combined with an aromatase inhibitor for initial endocrine-based therapy for treatment of postmenopausal women with hormone receptor positive, human epidermal growth factor receptor-2 negative (HR+/HER2-) advanced or metastatic breast cancer. It inhibits the growth of tumor cells by arresting the cells at the G1 checkpoint, which prevents the tumor cells from proliferating. In the phase III trial, it demonstrating statistically significant improvement in progression-free survival (PFS) compared to letrozole alone at the first pre-planned interim analysis.
1 India supplier list of "LEE011"
- Product Name:Ribociclib free base
- Products Intro:Purity: 98% | Package: 1 kg, 5 kg, 10 kg, 25kg and 1 MT
- Company Type: Manufacturer
- Country/Region: Hyderabad,INDIA
- Product Name:CDK4/6Inhibitor
- Products Intro:Brand:clearsynth | Product Number:CS-T-50416
- Company Type: Trader
- Country/Region: Hyderabad,INDIA
- Product Name:Ribociclib
- Products Intro:Purity: 98% HPLC | Package: 1g
- Company Type: Trader
- Country/Region: CHINA
- Main Products: Inosine pranobex,Probenecid,Sodium Ceftiofur,3-O-Ethyl-L-ascorbic acid,benzhexol hydrochloride
$0.00/ 1g
- Product Name:LEE011
- Products Intro:Purity: 99% | Package: 25KG;5KG;1KG
- Company Type: Trader
- Country/Region: CHINA
- Product Name:LEE-011
- Products Intro:Package: as customers' requirement
- Company Type: Trader
- Country/Region: CHINA
- Product Name:Ribociclib
- Products Intro:Purity: 98% | Package: 1KG;1USD
- Company Type: Reagent
- Country/Region: CHINA
- Main Products: Nicotinamide riboside chloride,Curcumin,L(+)-Ascorbic acid,L-Glutamine,Stevioside Basic information
$1.00/ 1KG
- Product Name:Ribociclib
- Products Intro:Purity: 0.98 | Package: 1kg，2kg，5kg，10kg，25kg
- Company Type: Trader
- Country/Region: CHINA
- Main Products: 2,7-ADA,2,4,6-Trichloroaniline,TRIMETHYLOXONIUM TETRAFLUOROBORATE,Zinc sulfide,5-HEXEN-1-OL
- Product Name:Ribociclib
- Products Intro:Purity: 99%
- Company Type: Trader
- Country/Region: CHINA
- Product Name:LEE011
- Products Intro:Purity: 99% | Package: USP EP CP
- Company Type: Trader
- Country/Region: CHINA
- Main Products: Pharmceutical,Optical Brightening,dyes