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LEE011

LEE011 Structure
CAS No.
1256963-02-6
Chemical Name:
LEE011
Synonyms
Rebosini;Ribociclib(LEE011);4-(5-Chloro-3-isopropyl-1H-pyrazol-4-yl)-N-(5-(4-(dimethylamino)piperidin-1-yl)pyridin-2-yl)pyrimidin-2-amine;CS-842;LEE011;CDK4-IN-1;CDK4 inhibitor;CDK4/6 inhibitor;LEE011 USP/EP/BP;Ribociclib Free Base
CBNumber:
CB42655411
Molecular Formula:
C22H29ClN8
Molecular Weight:
440.97
MOL File:
1256963-02-6.mol
MSDS File:
SDS
Modify Date:
2023/8/2 13:13:13
Request For Quotation

LEE011 Properties

Melting point >180°C (dec.)
Boiling point 679.3±65.0 °C(Predicted)
Density 1.31±0.1 g/cm3(Predicted)
storage temp. -20°C Freezer
solubility DMSO (Slightly), Methanol (Slightly)
pka 7.57±0.50(Predicted)
form Solid
color Beige

LEE011 Chemical Properties,Uses,Production

Uses

CDK 4/6 Inhibitor is a part of a group of compounds that exhibits selective inhibitory properties towards Cyclin-Dependent Kinases 4 & 6. These compounds are most commonly used to treat patients with breast cancer.

LEE011 Preparation Products And Raw materials

Raw materials

Preparation Products

LEE011 Suppliers

Global( 132)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6257 58 Inquiry
shandong perfect biotechnology co.ltd +86-53169958659 +86-13153181156 China 294 58 Inquiry
Henan Tianfu Chemical Co.,Ltd. +86-0371-55170693 +86-19937530512 China 21628 55 Inquiry
career henan chemical co +86-0371-86658258 +8613203830695 China 29858 58 Inquiry
Linyi Changqing Chemical Co., LTD +86-0532-55729510 +8615853232676 China 308 58 Inquiry
TargetMol Chemicals Inc. +1-781-999-5354 +1-00000000000 United States 32159 58 Inquiry
Hubei Ipure Biology Co., Ltd +8613367258412 China 10244 58 Inquiry
Dideu Industries Group Limited +86-29-89586680 +86-15129568250 China 22854 58 Inquiry
AFINE CHEMICALS LIMITED +86-0571-85134551 China 15395 58 Inquiry
Dayang Chem (Hangzhou) Co.,Ltd. +86-0571-88938639 +8617705817739 China 52849 58 Inquiry
Supplier Advantage
CLEARSYNTH LABS LTD. 58
shandong perfect biotechnology co.ltd 58
Henan Tianfu Chemical Co.,Ltd. 55
career henan chemical co 58
Linyi Changqing Chemical Co., LTD 58
TargetMol Chemicals Inc. 58
Hubei Ipure Biology Co., Ltd 58
Dideu Industries Group Limited 58
AFINE CHEMICALS LIMITED 58
Dayang Chem (Hangzhou) Co.,Ltd. 58

1256963-02-6(LEE011)Related Search:

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4-[[4-[[4-[(E)-2-cyanoethenyl]-2,6-dimethyl-phenyl]amino]pyrimidin-2-yl]amino]benzonitrile 1110813-31-4 918504-65-1
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LEE011 CDK4/6 inhibitor CDK4 inhibitor CDK4-IN-1 CDK 4/6 Inhibitor, >=98% Ribociclib(Lee011 & CDK 4/6 inhibitor) 4-[5-Chloro-3-(1-methylethyl)-1H-pyrazol-4-yl]-N-[5-[4-(dimethylamino)-1-piperidinyl]-2-pyridinyl]-2-pyrimidinamine 4-(3-chloro-5-propan-2-yl-1H-pyrazol-4-yl)-N-[5-[4-(dimethylamino)piperidin-1-yl]pyridin-2-yl]pyrimidin-2-amine Ribociclib Free Base 4-(5-Chloro-3-isopropyl-1H-pyrazol-4-yl)-N-(5-(4-(dimethylamino)piperidin-1-yl)pyridin-2-yl)py CS-842 2-Pyrimidinamine, 4-[3-chloro-5-(1-methylethyl)-1H-pyrazol-4-yl]-N-[5-[4-(dimethylamino)-1-piperidinyl]-2-pyridinyl]- LEE011 USP/EP/BP 4-(5-Chloro-3-isopropyl-1H-pyrazol-4-yl)-N-(5-(4-(dimethylamino)piperidin-1-yl)pyridin-2-yl)pyrimidin-2-amine Ribociclib(LEE011) Rebosini 1256963-02-6 C22H29ClN8 Inhibitors