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LEE011

CAS No.: 1256963-02-6

Chemical Name:: LEE011

Synonyms: Rebosini;Ribociclib(LEE011);4-(5-Chloro-3-isopropyl-1H-pyrazol-4-yl)-N-(5-(4-(dimethylamino)piperidin-1-yl)pyridin-2-yl)pyrimidin-2-amine;CS-842;LEE011;CDK4-IN-1;CDK4 inhibitor;CDK4/6 inhibitor;LEE011 USP/EP/BP;Ribociclib Free Base

CBNumber:: CB42655411

Molecular Formula:: C22H29ClN8

Molecular Weight:: 440.97

MOL File:: 1256963-02-6.mol

MSDS File:: SDS

Modify Date:: 2023/8/2 13:13:13

Request For Quotation

LEE011 Properties

Melting point	>180°C (dec.)
Boiling point	679.3±65.0 °C(Predicted)
Density	1.31±0.1 g/cm3(Predicted)
storage temp.	-20°C Freezer
solubility	DMSO (Slightly), Methanol (Slightly)
pka	7.57±0.50(Predicted)
form	Solid
color	Beige

LEE011 Chemical Properties,Uses,Production

Uses

CDK 4/6 Inhibitor is a part of a group of compounds that exhibits selective inhibitory properties towards Cyclin-Dependent Kinases 4 & 6. These compounds are most commonly used to treat patients with breast cancer.

LEE011 Preparation Products And Raw materials

Raw materials

Preparation Products

LEE011 Suppliers

Global( 119)Suppliers

Supplier	Tel	Country	ProdList	Advantage	Inquiry
CHEMAZON LABORATORIES	+91 9848551964	Hyderabad, India	1320	58	Inquiry
CLEARSYNTH LABS LTD.	+91-22-45045900	Hyderabad, India	6351	58	Inquiry
shandong perfect biotechnology co.ltd	+86-53169958659; +8618596095638	China	294	58	Inquiry
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	China	21668	55	Inquiry
Hangzhou FandaChem Co.,Ltd.	008657128800458; +8615858145714	China	9332	55	Inquiry
career henan chemical co	+86-0371-86658258 +8613203830695	China	29894	58	Inquiry
Chongqing Chemdad Co., Ltd	+86-023-6139-8061 +86-86-13650506873	China	39916	58	Inquiry
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	United States	19892	58	Inquiry
Hubei Ipure Biology Co., Ltd	+8613367258412	China	10326	58	Inquiry
Dideu Industries Group Limited	+86-29-89586680 +86-15129568250	China	24330	58	Inquiry

Supplier	Advantage
CHEMAZON LABORATORIES	58
CLEARSYNTH LABS LTD.	58
shandong perfect biotechnology co.ltd	58
Henan Tianfu Chemical Co.,Ltd.	55
Hangzhou FandaChem Co.,Ltd.	55
career henan chemical co	58
Chongqing Chemdad Co., Ltd	58
TargetMol Chemicals Inc.	58
Hubei Ipure Biology Co., Ltd	58
Dideu Industries Group Limited	58

1256963-02-6(LEE011)Related Search:

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Nintedanib PLX-4720 Alectinib Crizotinib Afatinib (BIBW 2992)

PLERIXAFOR Neratinib Ripasudil hydrochloride dihydrate Cabozantinib Malate Riociguat

4-[[4-[[4-[(E)-2-cyanoethenyl]-2,6-dimethyl-phenyl]amino]pyrimidin-2-yl]amino]benzonitrile 1110813-31-4 918504-65-1

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LEE011 CDK4/6 inhibitor CDK4 inhibitor CDK4-IN-1 CDK 4/6 Inhibitor, >=98% Ribociclib(Lee011 & CDK 4/6 inhibitor) 4-[5-Chloro-3-(1-methylethyl)-1H-pyrazol-4-yl]-N-[5-[4-(dimethylamino)-1-piperidinyl]-2-pyridinyl]-2-pyrimidinamine 4-(3-chloro-5-propan-2-yl-1H-pyrazol-4-yl)-N-[5-[4-(dimethylamino)piperidin-1-yl]pyridin-2-yl]pyrimidin-2-amine Ribociclib Free Base 4-(5-Chloro-3-isopropyl-1H-pyrazol-4-yl)-N-(5-(4-(dimethylamino)piperidin-1-yl)pyridin-2-yl)py CS-842 2-Pyrimidinamine, 4-[3-chloro-5-(1-methylethyl)-1H-pyrazol-4-yl]-N-[5-[4-(dimethylamino)-1-piperidinyl]-2-pyridinyl]- LEE011 USP/EP/BP 4-(5-Chloro-3-isopropyl-1H-pyrazol-4-yl)-N-(5-(4-(dimethylamino)piperidin-1-yl)pyridin-2-yl)pyrimidin-2-amine Ribociclib(LEE011) Rebosini 1256963-02-6 C22H29ClN8 Inhibitors