LEPTOMYCIN A
LEPTOMYCIN A
- CAS:
- 87081-36-5
- MF:
- C32H46O6
- MW:
- 526.7
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Properties
- Flash point:
- 9℃
- storage temp.
- -20°C
- solubility
- Ethanol: Soluble; Methanol: Soluble
- form
- methanol solution
- color
- Colorless to light yellow
Safety Information
- Symbol(GHS)
GHS02,GHS06,GHS08
- Signal word
- Danger
- Hazard statements
- H225-H301+H311+H331-H370
- Precautionary statements
- P210-P260-P280-P301+P310-P311
- Hazard Codes
- F,T
- Risk Statements
- 11-23/24/25-39/23/24/25
- Safety Statements
- 16-36/37-45
- RIDADR
- UN 1230 3/PG 2
- WGK Germany
- 1
- HS Code
- 3822000000
Use
Leptomycin A, a methyl analogue of leptomycin B, is a minor component of the leptomycin complex produced by selected Streptomyces species. Leptomycin B is a potent inhibitor of the nuclear transport receptor CRM1. Leptomycin A is also likely to inhibit nuclear transport and may offer differences in exporter selectivity. Leptomycin A shows antimicrobial activity against Schizosaccaromyces pombe and Mucor rouxianus.
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