Minocycline hydrochloride
Minocycline hydrochloride
- CAS:
- 13614-98-7
- MF:
- C23H28ClN3O7
- MW:
- 493.94
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Company Type
Properties
- Melting point:
- 205-210° (dec)
- Boiling point:
- 813℃
- Flash point:
- >110°(230°F)
- storage temp.
- 2-8°C
- solubility
- Sparingly soluble in water, slightly soluble in ethanol (96 per cent). It dissolves in solutions of alkali hydroxides and carbonates.
- form
- crystalline
- color
- yellow
- Water Solubility
- Freely soluble in water
- Merck
- 14,6202
- Stability:
- Light Sensitive
- InChIKey
- GLMUAFMGXXHGLU-VQAITOIOSA-N
- SMILES
- [C@@]12([H])C[C@@]3([H])C(C(=O)C4C(O)=CC=C(N(C)C)C=4C3)=C(O)[C@]1(O)C(=O)C(C(=O)N)=C(O)[C@H]2N(C)C.Cl |&1:0,3,21,31,r|
- LogP
- 0.808 (est)
Safety Information
- Symbol(GHS)
GHS07,GHS08
- Signal word
- Danger
- Hazard statements
- H317-H360-H362-H303-H315-H319-H335
- Precautionary statements
- P201-P202-P260-P263-P264-P270-P272-P280-P302+P352+P333+P313+P363-P308+P313-P405-P501-P261-P280a-P304+P340-P305+P351+P338-P501a
- Hazard Codes
- Xi
- Risk Statements
- 36/37/38
- Safety Statements
- 26-36
- RIDADR
- 3249
- WGK Germany
- 3
- RTECS
- QI7630500
- HazardClass
- 6.1(b)
- PackingGroup
- III
- HS Code
- 29413020
- Toxicity
- human,TDLo,oral,14286ug/kg/10 (14.286mg/kg),LUNGS, THORAX, OR RESPIRATION: RESPIRATORY OBSTRUCTIONLUNGS, THORAX, OR RESPIRATION: DYSPNEASKIN AND APPENDAGES (SKIN): "DERMATITIS, OTHER: AFTER SYSTEMIC EXPOSURE",Archives of Internal Medicine. Vol. 154, Pg. 1633, 1994.
Use
Minocycline hydrochloride is a salt prepared from minocycline, taking advantage of the two basic dimethylamino groups which protonate and readily form a salt from hydrochloric acid solutions. The hydrochloride is the preferred formulation for pharmaceutical applications. Like all tetracyclines, minocycline shows broad spectrum antibacterial and antiprotozoan activity and acts by binding to the 30S and 50S ribosomal sub-units, blocking protein synthesis.
13 India supplier list of "Minocycline hydrochloride"
- Product Name:Minocyclinehydrochloride
- Products Intro:Brand:sigma aldrich | Product Number:M9511 | Purity:powder
- Company Type: Trader
- Country/Region: Bangalore,INDIA
- Product Name:Minocycline hydrochloride >98% (HPLC)
- Products Intro:Brand：Glrinnovations | OriginalID：GLR19.070968
- Company Type: Trader
- Country/Region: New Delhi,INDIA
- Product Name:MinocyclineHydrochloride
- Products Intro:Brand:synzeal | Product Number:205154051
- Company Type: Trader
- Country/Region: Gujarat,INDIA
- Product Name:Minocycline hydrochloride
- Company Type: Reagent
- Country/Region: Hyderabad,INDIA
- Product Name:Minocyclinehydrochloride(Y0001930)
- Products Intro:Brand:clearsynth | Product Number:CS-EG-00514
- Company Type: Trader
- Country/Region: Hyderabad,INDIA
- Product Name:Minocycline hydrochloride
- Company Type: Reagent
- Country/Region: Maharashtra,INDIA
- Product Name:MinocyclineHydrochloride
- Products Intro:Brand:tcichemicals | Product Number:M2288
- Company Type: Reagent
- Country/Region: New Delhi,INDIA
- Product Name:Minocycline hydrochloride
- Company Type: Reagent
- Country/Region: Haryana,INDIA
- Product Name:Minocycline hydrochloride
- Company Type: Reagent
- Country/Region: Hyderabad,INDIA
- Product Name:Minocycline hydrochloride
- Company Type: Reagent
- Country/Region: Maharashtra,INDIA