Norepinephrine
Norepinephrine
- CAS:
- 51-41-2
- MF:
- C8H11NO3
- MW:
- 169.18
Suppliers by country/region
Company Type
Properties
- Melting point:
- 220-230°C
- alpha
- D25 -37.3° (c = 5 in water with 1 equiv HCl)
- Boiling point:
- 298.46°C (rough estimate)
- Density
- 1.2435 (rough estimate)
- refractive index
- 1.5100 (estimate)
- storage temp.
- 2-8°C
- solubility
- Aqueous Acid (Slightly), DMSO (Slightly)
- form
- crystalline
- pka
- 8.64(at 25℃)
- color
- off-white to tan
- optical activity
- D +37.426 (c 5, H2O+HCl)L -37.1325 (c 5, H2O+HCl)
- Water Solubility
- Soluble in alkali and dilute hydrochloric acid. Slightly soluble in water, ethanol and diethyl ether.
- Sensitive
- Air & Light Sensitive
- Merck
- 14,6695
- BRN
- 4231961
- Stability:
- Stable, but may be light-sensitive. Incompatible with acids, bases, oxidizing agents. Store at -20℃.
Safety Information
- Symbol(GHS)
GHS06
- Signal word
- Danger
- Hazard statements
- H300+H310+H330
- Precautionary statements
- P260-P262-P264-P280-P302+P352+P310-P304+P340+P310
- Hazard Codes
- T+,C,F
- Risk Statements
- 26/27/28-34-11-28
- Safety Statements
- 28-36/37-45-36/37/39-26-16-20
- RIDADR
- UN 2811 6.1/PG 2
- WGK Germany
- 3
- RTECS
- DN5950000
- F
- 8-10-23
- HazardClass
- 6.1
- PackingGroup
- II
- HS Code
- 29225090
- Toxicity
- dni-hmn:oth 5800 nmol/L CNREA8 40,1414,80
Use
Norepinephrine (NE, Levophed) differs from DA onlyby addition of a 1-OH substituent (β-OH-DA) and from Eonly by lacking the N-methyl group. Like DA, it is polar andrapidly metabolized by both COMT and MAO, resulting inpoor oral bioavailability and short DOA (1 or 2 minutes evenwhen given intravenously). It is a stimulant of α1-, α2-, andβ1-adrenoceptors (notice that lacking the N-methyl group resultsin lacking β2- and β3-activity). It is used to counteractvarious hypotensive crises, because its α-activity raisesblood pressure and as an adjunct treatment in cardiac arrestbecause its β-activity stimulates the heart. It has limitedclinical application caused by the nonselective nature of itsactivities.
12 India supplier list of "Norepinephrine"
- Product Name:(R)-(-)-Norepinephrine
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Reagent
- Country/Region: INDIA
- Product Name:Adrenaline EP Impurity B
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Manufacturer
- Country/Region: INDIA
- Product Name:(R)-(-)-Norepinephrine
- Products Intro:Purity: 99% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Manufacturer
- Country/Region: INDIA
- Product Name:(R)-(-)-Norepinephrine
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg
- Company Type: Manufacturer
- Country/Region: INDIA
- Product Name:(−)-Norepinephrine
- Products Intro:Brand:sigma aldrich | Product Number:A7257 | Purity:≥98%,crystalline
- Company Type: Trader
- Country/Region: INDIA
- Product Name:Norepinephrine
- Company Type: Trader
- Country/Region: INDIA
- Product Name:Norepinephrine
- Company Type: Reagent
- Country/Region: INDIA
- Product Name:Norepinephrine
- Company Type: Reagent
- Country/Region: INDIA
- Product Name:Noradrenaline
- Products Intro:Brand:pharmaffiliates | Product Number:PA0127020
- Company Type: Trader
- Country/Region: INDIA
- Product Name:Norepinephrine
- Company Type: Reagent
- Country/Region: INDIA