Phenylephrine
Phenylephrine
- CAS:
- 59-42-7
- MF:
- C9H13NO2
- MW:
- 167.21
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Company Type
Properties
- Melting point:
- 171°C
- Boiling point:
- 295.79°C (rough estimate)
- Density
- 1.1222 (rough estimate)
- refractive index
- -55.5 ° (C=5, 1mol/L HCl)
- storage temp.
- -20°C Freezer, Under inert atmosphere
- solubility
- Slightly soluble in water, sparingly soluble in methanol, slightly soluble in ethanol (96 per cent). It dissolves in dilute mineral acids and in dilute solutions of alkali hydroxides.
- form
- Solid
- pka
- pKa 8.9 (Uncertain)
- color
- White to Off-White
Safety Information
- Symbol(GHS)
GHS05,GHS07
- Signal word
- Danger
- Hazard statements
- H302-H315-H318-H335
- Precautionary statements
- P261-P264-P280-P301+P312-P302+P352-P305+P351+P338
- Hazard Codes
- Xn
- Risk Statements
- 22-36/37/38-41-37/38
- Safety Statements
- 26-36-45-39
- RTECS
- DO7175000
- HS Code
- 2922.19.7000
- Toxicity
- LD50 oral in rat: 350mg/kg
Use
L-Phenylephrine is an adrenergic α1A receptor agonist (Ki = 1.4 μM) that demonstrates selectivity against the α1B and α1C receptor subtypes (Kis = 23.9 and 47.8 μM, respectively). By stimulating adrenergic α1 receptors, L-phenylephrine can induce aortic smooth muscle contractions, although reported relative affinity and potency values in rabbit are 5-fold weaker compared to that of L-norepinephrine. This compound is frequently used to precontract smooth muscle in preparations designed to study the properties of various vasodilator agents. Because L-phenylephrine acts on adrenergic α1 receptors in the arterioles of the nasal mucosa to produce constriction, it has been examined clinically as an oral decongestant.
22 India supplier list of "Phenylephrine"
- Product Name:(R)-Phenylephrine
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg
- Company Type: Manufacturer
- Country/Region: Maharashtra,INDIA
- Product Name:PHENYLEPHRINE
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Manufacturer
- Country/Region: Hyderabad,INDIA
- Product Name:(R)-Phenylephrine
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Manufacturer
- Country/Region: Karnataka,INDIA
- Product Name:(R)-Phenylephrine
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg And 1MT
- Company Type: Manufacturer
- Country/Region: Maharashtra,INDIA
- Product Name:Phenylephrine
- Products Intro:Brand:synzeal | Product Number:110408324
- Company Type: Trader
- Country/Region: Gujarat,INDIA
- Product Name:Phenylephrine
- Company Type: Reagent
- Country/Region: Maharashtra,INDIA
- Product Name:Phenyl Ephrine
- Company Type: Reagent
- Country/Region: Kolkata,INDIA
- Product Name:Phenylephrine
- Company Type: Reagent
- Country/Region: Haryana,INDIA
- Product Name:Phenylephrine
- Company Type: Reagent
- Country/Region: Andhra Pradesh,INDIA