Sulfapyridine
Sulfapyridine
- CAS:
- 144-83-2
- MF:
- C11H11N3O2S
- MW:
- 249.29
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Company Type
Properties
- Melting point:
- 191-193°C
- Boiling point:
- 473.5±51.0 °C(Predicted)
- Density
- 1.3220 (rough estimate)
- refractive index
- 1.6740 (estimate)
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- solubility
- DMSO (Slightly), Methanol (Slightly)
- pka
- pKa 8.48(H2O t = 25 I = 0.05) (Uncertain)
- form
- Solid
- color
- White to Off-White
- Water Solubility
- <0.1 g/100 mL at 22 ºC
- Merck
- 14,8938
- BRN
- 222065
- Stability:
- Stable. Combustible. Protect from light. Incompatible with strong oxidizing agents.
Safety Information
- Symbol(GHS)
GHS08
- Signal word
- Warning
- Hazard statements
- H361fd
- Precautionary statements
- P201-P202-P280-P308+P313-P405-P501
- Hazard Codes
- Xi
- Risk Statements
- 36/37/38
- Safety Statements
- 22-24/25-36-26
- WGK Germany
- 2
- RTECS
- DA9625000
- HazardClass
- IRRITANT
- HS Code
- 29350010
- Toxicity
- LD50 orally in mice: 7.5 mg/g (Wien)
Use
Sulfapyridine’s plasma half-life is 9 hours.This compound is a white, crystalline, odorless, and tastelesssubstance. It is stable in air but slowly darkens on exposureto light. It is soluble in water (1:3,500), in alcohol(1:440), and in acetone (1:65) at 25°C. It is freely soluble indilute mineral acids and aqueous solutions of sodium andpotassium hydroxide. The pKa is 8.4. Its outstanding effectin curing pneumonia was first recognized by Whitby; however,because of its relatively high toxicity, it has been supplantedlargely by sulfadiazine and sulfamerazine. Severalcases of kidney damage have resulted from acetylsulfapyridinecrystals deposited in the kidneys. It also causes severenausea in most patients. Because of its toxicity, it is usedonly for dermatitis herpetiformis.Sulfapyridine was the first drug to have an outstandingcurative action on pneumonia. It gave impetus to the studyof the whole class of N1 heterocyclically substituted derivativesof sulfanilamide.
21 India supplier list of "Sulfapyridine"
- Product Name:Sulfapyridine
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg And 1MT
- Company Type: Manufacturer
- Country/Region: INDIA
- Product Name:Sulfapyridine
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg
- Company Type: Reagent
- Country/Region: INDIA
- Product Name:Sulfapyridine
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Manufacturer
- Country/Region: INDIA
- Product Name:Sulfasalazine EP Impurity-J
- Products Intro:Purity: 98% | Package: 50 MG; 100 MG; 250 MG ; 100 MG
- Company Type: Manufacturer
- Country/Region: INDIA
- Product Name:SULPHAPYRIDINE
- Products Intro:Purity: 99% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Manufacturer
- Country/Region: INDIA
- Product Name:Sulfapyridine
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Reagent
- Country/Region: INDIA
- Product Name:Sulfapyridine
- Products Intro:Brand:sigma aldrich | Product Number:31738 | Purity:VETRANAL?,analyticalstandard
- Company Type: Trader
- Country/Region: INDIA
- Product Name:Sulfapyridine
- Company Type: Reagent
- Country/Region: INDIA