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11-[[2-[(DIETHYLAMINO)METHYL]-1-PIPERIDINYL]ACETYL]-5,11-DIHYDRO-6H-PYRIDO[2,3-B][1,4]BENZODIAZEPIN-6-ONE

11-[[2-[(DIETHYLAMINO)METHYL]-1-PIPERIDINYL]ACETYL]-5,11-DIHYDRO-6H-PYRIDO[2,3-B][1,4]BENZODIAZEPIN-6-ONE Structure
  • ₹10846.65 - ₹43527.33
  • Product name: 11-[[2-[(DIETHYLAMINO)METHYL]-1-PIPERIDINYL]ACETYL]-5,11-DIHYDRO-6H-PYRIDO[2,3-B][1,4]BENZODIAZEPIN-6-ONE
  • CAS: 102394-31-0
  • MF: C24H31N5O2
  • MW: 421.54
  • EINECS:
  • MDL Number:MFCD00864743
  • Synonyms:11-[[2-[(DIETHYLAMINO)METHYL]-1-PIPERIDINYL]ACETYL]-5,11-DIHYDRO-6H-PYRIDO[2,3-B][1,4]BENZODIAZEPIN-6-ONE;AF-DX 116;6h-pyrido(2,3-b)(1,4)benzodiazepin-6-one,5,11-dihydro-11-((2-((diethylamino)m ;ethyl)-7-piperidinyl)acetyl)- ;11-((2-((Diethylamino)methyl)-1-piperidinyl)acetyl)-5,11-dihydro-(6H)-pyrido[2.3-b][1.4]benzodiazepin-6-one;6H-Pyrido(2,3-B)(1,4)benzodiazepin-6-one, 11-((2-((diethylamino)methyl)-1-piperidinyl)acetyl)-5,11-dihydro-;6H-Pyrido(2,3-B)(1,4)benzodiazepin-6-one, 5,11-dihydro-11-((2-((diethylamino)methyl)-7-piperidinyl)acetyl)-;Brn 4212983
3 prices
Selected condition:

Brand

  • Sigma-Aldrich(India)

Package

  • 5MG
  • 10MG
  • 25MG
  • ManufacturerSigma-Aldrich(India)
  • Product numberSML0435
  • Product descriptionAF-DX 116 ≥98% (HPLC)
  • Packaging5MG
  • Price₹10846.65
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number5.05821
  • Product descriptionAF-DX 116 - CAS 102394-31-0 - Calbiochem
  • Packaging10MG
  • Price₹18740
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberSML0435
  • Product descriptionAF-DX 116 ≥98% (HPLC)
  • Packaging25MG
  • Price₹43527.33
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) SML0435 AF-DX 116 ≥98% (HPLC) 5MG ₹10846.65 2022-06-14 Buy
Sigma-Aldrich(India) 5.05821 AF-DX 116 - CAS 102394-31-0 - Calbiochem 10MG ₹18740 2022-06-14 Buy
Sigma-Aldrich(India) SML0435 AF-DX 116 ≥98% (HPLC) 25MG ₹43527.33 2022-06-14 Buy

Properties

Boiling point :573.2±45.0 °C(Predicted)
Density :1.171
storage temp. :room temp
solubility :DMSO: soluble5mg/mL (clear solution; warmed)
pka :11.29±0.20(Predicted)
form :powder
color :white to beige

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P233 Keep container tightly closed.
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P304 IF INHALED:
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P312 Call a POISON CENTER or doctor/physician if you feel unwell.
P321 Specific treatment (see … on this label).
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P337+P313 IF eye irritation persists: Get medical advice/attention.
P340 Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P362 Take off contaminated clothing and wash before reuse.
P403 Store in a well-ventilated place.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

AF-DX 116 is a selective mAChR M2 antagonist. Ki values are 64, 417, 786, 211 and 5130 nM for human recombinant M2, M1, M3, M4 and M5 muscarinic receptors, respectively.

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