2,2-Dimethyl-N-(2,4,6-trimethoxyphenyl)dodecanamide
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- ₹16518.95
- Product name: 2,2-Dimethyl-N-(2,4,6-trimethoxyphenyl)dodecanamide
- CAS: 114289-47-3
- MF: C23H39NO4
- MW: 393.56
- EINECS:
- MDL Number:MFCD00869662
- Synonyms:2,2-dimethyl-n-(2,4,6-trimethoxyphenyl)-dodecanamid ;2,2-DIMETHYL-N-(2,4,6-TRIMETHOXYPHENYL)DODECANAMIDE;CI 976;PD 128042;N-(2,4,6-Trimethoxyphenyl)-2,2-dimethyldodecanamide;CI-976 (PD 128042);Dodecanamide, 2,2-dimethyl-N-(2,4,6-trimethoxyphenyl)-;inhibit,oral,PD128042,PD 128042,CI-976,Diacylglycerol acyltransferase,PD-128042,Acyltransferase,transferase,secretory,LPAT,acyl-CoA:cholesterol acyltransferase,mono- acylglycerol acyltransferase,endocytic membrane trafficking pathway,ACAT,CI976,Diglyceride acyltransferase,Inhibitor
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Selected condition:
Brand
- Sigma-Aldrich(India)
Package
- 5MG
- ManufacturerSigma-Aldrich(India)
- Product numberC3743
- Product descriptionCI 976 >98% (HPLC), solid
- Packaging5MG
- Price₹16518.95
- Updated2022-06-14
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
Sigma-Aldrich(India) | C3743 | CI 976 >98% (HPLC), solid | 5MG | ₹16518.95 | 2022-06-14 | Buy |
Properties
storage temp. :2-8°C
solubility :DMSO: >10mg/mL
form :solid
color :White to off-white
InChI :InChI=1S/C23H39NO4/c1-7-8-9-10-11-12-13-14-15-23(2,3)22(25)24-21-19(27-5)16-18(26-4)17-20(21)28-6/h16-17H,7-15H2,1-6H3,(H,24,25)
InChIKey :WAFNZAURAWBNDZ-UHFFFAOYSA-N
SMILES :C(NC1=C(OC)C=C(OC)C=C1OC)(=O)C(C)(C)CCCCCCCCCC
solubility :DMSO: >10mg/mL
form :solid
color :White to off-white
InChI :InChI=1S/C23H39NO4/c1-7-8-9-10-11-12-13-14-15-23(2,3)22(25)24-21-19(27-5)16-18(26-4)17-20(21)28-6/h16-17H,7-15H2,1-6H3,(H,24,25)
InChIKey :WAFNZAURAWBNDZ-UHFFFAOYSA-N
SMILES :C(NC1=C(OC)C=C(OC)C=C1OC)(=O)C(C)(C)CCCCCCCCCC
Safety Information
Symbol(GHS): |
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Description
Acyl-coenzyme A:cholesterol acyltransferase 1 (ACAT-1) is a sterol O-acyltransferase that catalyzes the formation of fatty acid-cholesterol esters, an important step in lipoprotein assembly and dietary cholesterol absorption. CI-976 is a potent, selective inhibitor of ACAT-1 (IC50 = 73 nM). It is orally bioavailable and decreases plasma total cholesterol, very low density lipoprotein (VLDL) cholesterol, LDL cholesterol, apolipoprotein B, liver cholesteryl esters, and VLDL and LDL cholesteryl ester content in rabbits given a diet that induces hypercholesterolemia. CI-976 also diminishes atherosclerotic activity in hypercholesterolemic rabbits.Related product price
- 114289-47-3
₹16518.95 - 2,6-DIMETHOXYANILINE
₹2982-18414 - Dodecanamide
₹4500-49800
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