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(S)-3-PHENYL-2-[(PYRAZIN-2-YLCARBONYL)AMINO] PROPANOIC ACID

(S)-3-PHENYL-2-[(PYRAZIN-2-YLCARBONYL)AMINO] PROPANOIC ACID Structure
  • ₹9500
  • Product name: (S)-3-PHENYL-2-[(PYRAZIN-2-YLCARBONYL)AMINO] PROPANOIC ACID
  • CAS: 114457-94-2
  • MF: C14H13N3O3
  • MW: 271.27
  • EINECS:
  • MDL Number:MFCD09800536
  • Synonyms:(S)-3-Phenyl-2-[(pyrazine-2-carbonyl)-amino]-propionic acid;Bortezomib Intermediate 2;N-Pyrazinylcarbonyl-L-phenylalanine;N-(2-Pyrazinylcarbonyl)-L-phenylalanine;Bortezomib Acid Impurity;Bortezomib INT B;N-(Pyrazinylcarbonyl)-L-phenylalanine;(S)-3-Phenyl-2-(pyrazine-2-carboxaMido)propanoic acid
Price1 Properties Safety Information Description
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Brand

  • TCI Chemicals (India)

Package

  • 1G
  • ManufacturerTCI Chemicals (India)
  • Product numberP2068
  • Product descriptionN-(Pyrazinylcarbonyl)-L-phenylalanine
  • Packaging1G
  • Price₹9500
  • Updated2022-05-26
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
TCI Chemicals (India) P2068 N-(Pyrazinylcarbonyl)-L-phenylalanine 1G ₹9500 2022-05-26 Buy

Properties

Melting point :166-169℃
Boiling point :573.8±50.0 °C(Predicted)
Density :1.323
storage temp. :Sealed in dry,Room Temperature
solubility :DMSO, Methanol (Sparingly)
pka :13.93±0.46(Predicted)
form :Solid
color :White to Light Beige

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

(S)-3-PHENYL-2-[(PYRAZIN-2-YLCARBONYL)AMINO] PROPANOIC ACID is used for the synthesis of Bortezomib (B675700) from L-phenylalanine via dipeptidyl boronic acid ester intermediates.

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Suppliers and manufacturers

OPULENT PHARMA Anant Pharmaceuticals Pvt Ltd PRODIGIOUS LIFE SCIENCES SYNARTIS PHARMA PVT LTD RANI LIFE SCIENCES PVT LTD VGS SYNTHESIS PRIVATE LIMITED Sai Teja Drugs and Intermediates Pvt Ltd RS LIFE SCIENCES TCI Chemicals (India) Pvt. Ltd. CLEARSYNTH LABS LTD.