4-[6-[4-(1-Methylethoxy)phenyl]pyrazolo[1,5-a]pyrimidin-3-yl]-quinoline
![4-[6-[4-(1-Methylethoxy)phenyl]pyrazolo[1,5-a]pyrimidin-3-yl]-quinoline Structure](/CAS/GIF/1206711-16-1.gif)
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- ₹7800 - ₹48788.28
- Product name: 4-[6-[4-(1-Methylethoxy)phenyl]pyrazolo[1,5-a]pyrimidin-3-yl]-quinoline
- CAS: 1206711-16-1
- MF: C24H20N4O
- MW: 380.44
- EINECS:
- MDL Number:MFCD18384963
- Synonyms:4-[6-[4-(1-Methylethoxy)phenyl]pyrazolo[1,5-a]pyrimidin-3-yl]-quinoline;Quinoline, 4-[6-[4-(1-methylethoxy)phenyl]pyrazolo[1,5-a]pyrimidin-3-yl]-;4-[6-[4-(1-Methylethoxy)phenyl]pyrazolo[1,5-a]pyrimidin-3-yl]quinoline DMH 1;DMH 1 4-[6-[4-(1-Methylethoxy)phenyl]pyrazolo[1,5-a]pyrimidin-3-yl]quinoline;4-[6-(4-Isopropoxyphenyl)pyrazolo[1,5-a]pyrimidin-3-yl]quinoline;DMH-1, >=98%;4-[6-(4-propan-2-yloxyphenyl)pyrazolo[1,5-a]pyrimidin-3-yl]quinoline;DMH-1(VU036482)
5 prices
Selected condition：
Brand
- TCI Chemicals (India)
- Sigma-Aldrich(India)
Package
- 5MG
- 10MG
- 25MG
- 50MG
- ManufacturerTCI Chemicals (India)
- Product numberD5737
- Product descriptionDMH-1
- Packaging10MG
- Price₹7800
- Updated2022-05-26
- Buy
- ManufacturerTCI Chemicals (India)
- Product numberD5737
- Product descriptionDMH-1
- Packaging50MG
- Price₹23900
- Updated2022-05-26
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberD8946
- Product descriptionDMH1 ≥98% (HPLC)
- Packaging5MG
- Price₹10446.13
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product number203646
- Product descriptionBMP Inhibitor II, DMH1 - CAS 1206711-16-1 - Calbiochem The BMP Inhibitor II, DMH1, also referenced under CAS 1206711-16-1, controls the biological activity of BMP. This small molecule/inhibitor is primaril
- Packaging5MG
- Price₹15469.99
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberD8946
- Product descriptionDMH1 ≥98% (HPLC)
- Packaging25MG
- Price₹48788.28
- Updated2022-06-14
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| TCI Chemicals (India) | D5737 | DMH-1 | 10MG | ₹7800 | 2022-05-26 | Buy |
| TCI Chemicals (India) | D5737 | DMH-1 | 50MG | ₹23900 | 2022-05-26 | Buy |
| Sigma-Aldrich(India) | D8946 | DMH1 ≥98% (HPLC) | 5MG | ₹10446.13 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 203646 | BMP Inhibitor II, DMH1 - CAS 1206711-16-1 - Calbiochem The BMP Inhibitor II, DMH1, also referenced under CAS 1206711-16-1, controls the biological activity of BMP. This small molecule/inhibitor is primaril | 5MG | ₹15469.99 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | D8946 | DMH1 ≥98% (HPLC) | 25MG | ₹48788.28 | 2022-06-14 | Buy |
Properties
Melting point :178 °C
Density :1.24±0.1 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: soluble5mg/mL, clear (warmed)
pka :3.34±0.46(Predicted)
form :powder
color :light yellow to orange
Density :1.24±0.1 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: soluble5mg/mL, clear (warmed)
pka :3.34±0.46(Predicted)
form :powder
color :light yellow to orange
Safety Information
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Description
Bone morphogenetic proteins (BMP) are secreted signaling proteins, many of which are involved in various developmental processes, in addition to bone formation. DMH1 is an analog of the non-selective BMP receptor inhibitor dorsomorphin that potently inhibits the kinase activity of activin receptor-like kinase 2 (ALK2; IC50 = 13-108 nM). It is much less effective at ALK4, ALK5, AMPK, KDR (VEGFR2) or PDGFRβ, although it inhibits ALK1 and ALK3 at nanomolar concentrations. DMH1 is effective in vivo, as it disrupts dorsoventral development in zebrafish. It also affects stem cell development, increasing cardiomyocyte progenitors and promoting neurogenesis. DMH1 inhibits the growth of lung cancer cells, reducing tumor growth in a xenograft mouse model.More related product prices
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![4-[6-[4-(1-Methylethoxy)phenyl]pyrazolo[1,5-a]pyrimidin-3-yl]-quinoline](https://img.chemicalbook.com/ProductImageEN/2019-12/small/9f6db54e-092a-41d9-ab18-d369af1d6993.png){kind=small}