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5,7-DICHLOROKYNURENIC ACID SODIUM SALT

5,7-DICHLOROKYNURENIC ACID SODIUM SALT Structure
  • ₹0
  • Product name: 5,7-DICHLOROKYNURENIC ACID SODIUM SALT
  • CAS: 131123-76-7
  • MF: C10H5Cl2NO3
  • MW: 258.06
  • EINECS:
  • MDL Number:MFCD00083173
  • Synonyms:5,7-DCKA;5,7-DICHLORO-4-HYDROXYQUINOLINE-2-CARBOXYLIC ACID;5,7-DICHLOROKYNURENIC ACID;5,7-DICHLOROKYNURENIC ACID SODIUM SALT;5,7-DICHLORO-4-HYDROXYQUINOLINE-2-CARBOXYLIC ACID NA;5,7-dichlorokynurenic acid sodium;2-Quinolinecarboxylic acid, 5,7-dichloro-4-hydroxy-;5,7-Dichorokynurenic acid
Properties Safety Information Description
Manufacturer Product number Product description Packaging Price Updated Buy

Properties

Boiling point :488.5±45.0 °C(Predicted)
Density :1.701±0.06 g/cm3(Predicted)
storage temp. :Desiccate at RT
solubility :0.1 M NaOH: soluble
form :solid
pka :3.30±0.40(Predicted)
color :light yellow
CAS DataBase Reference :131123-76-7(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

5,7-Dichlorokynurenic acid is a derivative of the excitatory amino acid kynurenic acid and an antagonist of the strychnine-insensitive glycine modulatory (co-agonist) binding site on the NMDA receptor. 5,7-Dichlorokynurenic acid is described to potently and noncompetitively antagonize NMDA-stimulated elevation of cytosolic Ca2+, accumulation of cGMP, and release of norepinephrine. 5,7-Dichlorokynurenic acid is an inhibitor of GluR.

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Suppliers and manufacturers

A.J Chemicals
TargetMol Chemicals Inc.
Career Henan Chemica Co
Aladdin Scientific HangZhou YuHao Chemical Technology Co., Ltd. Shanghai Aladdin Biochemical Technology Co.,Ltd. RD International Technology Co., Limited Bide Pharmatech Ltd. Taizhou Nanfeng Pharmaceutical Research Institute Wuhan graphe Pharmaceutical Technology Co., Ltd.