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ChemicalBook > Product Catalogue >API >Circulatory system drugs >Angina Pectoris Drugs >Trimetazidine dihydrochloride

Trimetazidine dihydrochloride

Trimetazidine dihydrochloride Structure
  • ₹11712.65 - ₹20664.93
  • Product name: Trimetazidine dihydrochloride
  • CAS: 13171-25-0
  • MF: C14H24Cl2N2O3
  • MW: 339.26
  • EINECS:236-117-0
  • MDL Number:MFCD00243086
  • Synonyms:1-(2,3,4-TRIMETHOXYBENZYL)PIPERAZINE DIHYDROCHLORIDE;1-[(2,3,4-Trimethoxy-phenyl)methyl]piperazine Dihydrochloride;Vastarel F;Yoshimilon;1-(2,3,4-Trimethoxybenzyl)piperazine dihydrochloride,Trimetazidine dihydrochloride;Trimetazidine 3HCl;Takkmint;Youmetazine
Price2 Properties Safety Information Description
2 prices
Selected condition：

Brand

  • Sigma-Aldrich(India)

Package

  • 10G
  • 25G
  • ManufacturerSigma-Aldrich(India)
  • Product number653322
  • Product description1-(2,3,4-Trimethoxybenzyl)piperazine dihydrochloride 97%
  • Packaging10G
  • Price₹11712.65
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number653322
  • Product description1-(2,3,4-Trimethoxybenzyl)piperazine dihydrochloride 97%
  • Packaging25G
  • Price₹20664.93
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) 653322 1-(2,3,4-Trimethoxybenzyl)piperazine dihydrochloride 97% 10G ₹11712.65 2022-06-14 Buy
Sigma-Aldrich(India) 653322 1-(2,3,4-Trimethoxybenzyl)piperazine dihydrochloride 97% 25G ₹20664.93 2022-06-14 Buy

Properties

Melting point :231-235 °C(lit.)
storage temp. :Refrigerator
solubility :Freely soluble in water, sparingly soluble in alcohol.
form :Solid
color :White to Off-White
Merck :14,9705
Stability :Hygroscopic
InChIKey :XIRALXKCBGTYSC-UHFFFAOYSA-N
CAS DataBase Reference :13171-25-0(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Trimetazidine dihydrochloride is the dihydrochloride salt of Trimetazidine. It is a drug used for the treatment of angina pectoris. It is capable of improving the left ventricular function in diabetic patients suffering coronary heart disease as well as treating the symptoms of patients suffering heart failure of different etiologies. It takes effects through acting as an anti- ischemic metabolic agent being capable of improving the utilization efficiency of myocardial glucose by inhibiting the metabolism of fatty acid (through inhibiting the activity of mitochondrial long- chain 3-ketoacyl coenzyme A Thiolase). The shift from fatty acid oxidation to glucose oxidation optimizes cellular energy process in cells exposed to hypoxia or ischaemia, further maintaining the intracellular ATP levels and ensuring the normal function of ionic pumps and transmembrane sodium-potassium flow to maintain cellular homeostasis.

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Suppliers and manufacturers

Jigs Chemical ltd chakrachem Lifesciences Prajna generics pvt ltd Varanous Labs Pvt Ltd JPN Pharma Pvt Ltd Technodrugs Intermediates Pvt. Ltd. Sharon Bio Medicine Ltd Aragen Life Sciences Pvt. Ltd. Rivashaa Agrotech Biopharma Pvt. Ltd. Tivan Sciences Pvt Ltd