Daunorubicin hydrochloride
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- ₹3972.78 - ₹28718.73
- Product name: Daunorubicin hydrochloride
- CAS: 23541-50-6
- MF: C27H29NO10.ClH
- MW: 563.98
- EINECS:245-723-4
- MDL Number:MFCD04974507
- Synonyms:5,12-Naphthacenedione,8-acetyl-10-[(3-aMino-2,3,6-trideoxy-a-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-Methoxy-,hydrochloride (1:1), (8S,10S)-;daunoblastin ;daunoblastina ;daunomycinchlorohydrate ;ndc0082-4155 ;ondena ;rp13057hydrochloride ;rubidomycinhydrochloride
6 prices
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Brand
- TCI Chemicals (India)
- Sigma-Aldrich(India)
Package
- 1MG
- 5MG
- 10MG
- 20MG
- 25MG
- 100MG
- ManufacturerTCI Chemicals (India)
- Product numberD4532
- Product descriptionDaunorubicin Hydrochloride
- Packaging20MG
- Price₹4700
- Updated2022-05-26
- Buy
- ManufacturerTCI Chemicals (India)
- Product numberD4532
- Product descriptionDaunorubicin Hydrochloride
- Packaging100MG
- Price₹10800
- Updated2022-05-26
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberD8809
- Product descriptionDaunorubicin hydrochloride meets USP testing specifications
- Packaging1MG
- Price₹3972.78
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product number30450
- Product descriptionDaunorubicin hydrochloride ≥90% (HPLC)
- Packaging5MG
- Price₹12621.95
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberD8809
- Product descriptionDaunorubicin hydrochloride meets USP testing specifications
- Packaging10MG
- Price₹17449.9
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product number30450
- Product descriptionDaunorubicin hydrochloride ≥90% (HPLC)
- Packaging25MG
- Price₹28718.73
- Updated2022-06-14
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
TCI Chemicals (India) | D4532 | Daunorubicin Hydrochloride | 20MG | ₹4700 | 2022-05-26 | Buy |
TCI Chemicals (India) | D4532 | Daunorubicin Hydrochloride | 100MG | ₹10800 | 2022-05-26 | Buy |
Sigma-Aldrich(India) | D8809 | Daunorubicin hydrochloride meets USP testing specifications | 1MG | ₹3972.78 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | 30450 | Daunorubicin hydrochloride ≥90% (HPLC) | 5MG | ₹12621.95 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | D8809 | Daunorubicin hydrochloride meets USP testing specifications | 10MG | ₹17449.9 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | 30450 | Daunorubicin hydrochloride ≥90% (HPLC) | 25MG | ₹28718.73 | 2022-06-14 | Buy |
Properties
Melting point :190°C (dec)
alpha :D20 +248 ±5° (c = 0.05-0.1 in methanol)
storage temp. :Inert atmosphere,2-8°C
solubility :Freely soluble in water and in methanol, slightly soluble in alcohol, practically insoluble in acetone.
form :solid
color :red to deep red
Water Solubility :Soluble in water (50 mM)
λmax :477nm(H2O)(lit.)
Sensitive :Hygroscopic
Merck :14,2832
BRN :4229221
Stability :Stability
EPA Substance Registry System :Daunorubicin hydrochloride (23541-50-6)
alpha :D20 +248 ±5° (c = 0.05-0.1 in methanol)
storage temp. :Inert atmosphere,2-8°C
solubility :Freely soluble in water and in methanol, slightly soluble in alcohol, practically insoluble in acetone.
form :solid
color :red to deep red
Water Solubility :Soluble in water (50 mM)
λmax :477nm(H2O)(lit.)
Sensitive :Hygroscopic
Merck :14,2832
BRN :4229221
Stability :Stability
EPA Substance Registry System :Daunorubicin hydrochloride (23541-50-6)
Safety Information
Symbol(GHS): |
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Description
Daunorubicin is an antitumor antibiotic widely used in the treatment of acute myeloid leukemias (AMLs). At 0.2-1μM, daunorubicin induces apoptosis in mature monocytic U937 and myelocytic HL-60 AML cells. However, immature AML cells (CD 34+-KG1a, -KG1, or -HEL cells) appear resistant to apoptosis at similar concentrations. In mature AML cells, daunorubicin has been shown to trigger a ROS-dependent sphingomyelin-ceramide pathway that activates the MEKK1-SEK1-JNK cascade leading to enhanced DNA binding activity of the transcription factor AP-1.More related product prices
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