N-[(S)-(2,3,4,5,6-pentafluorophenoxy)phenoxyphosphinyl]-L-alanine 1-Methylethyl ester
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- Product name: N-[(S)-(2,3,4,5,6-pentafluorophenoxy)phenoxyphosphinyl]-L-alanine 1-Methylethyl ester
- CAS: 1334513-02-8
- MF: C18H17F5NO5P
- MW: 453.3
- EINECS:695-076-0
- MDL Number:MFCD22665799
- Synonyms:1. (S)-isopropyl2-(((S)-(perfluorophenoxy)(phenoxy)phosphoryl);N-[(S)-(2,3,4,5,6-pentafluorophenoxy)phenoxyphosphinyl]-L-alanine 1-Methylethyl ester (SIDE CHAIN);L-Alanine, N-[(S)-(2,3,4,5,6-pentafluorophenoxy)phenoxyphosphinyl]-, 1-methylethyl ester;propan-2-yl (2S)-2-{[(S)-pentafluorophenoxy(phenoxy)phosphoryl]amino}propanoate;Sofosbuvir side chain N-1;Sofosbuvir Intermediate 5;isopropyl ((S)-(perfluorophenoxy)(phenoxy)phosphoryl)-L-alaninate;N-[(S)-(2,3,4,5,6-pentafluorophenoxy)phenoxyphosphinyl]-L-alanine 1-Methylethyl ester
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Properties
Melting point :133-135°C
Boiling point :442.6±55.0 °C(Predicted)
Density :1.405
vapor pressure :0Pa at 25℃
storage temp. :2-8°C
solubility :Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
pka :-3.81±0.70(Predicted)
form :Solid
color :White
LogP :4.1 at 30℃ and pH7.37
Boiling point :442.6±55.0 °C(Predicted)
Density :1.405
vapor pressure :0Pa at 25℃
storage temp. :2-8°C
solubility :Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
pka :-3.81±0.70(Predicted)
form :Solid
color :White
LogP :4.1 at 30℃ and pH7.37
Safety Information
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Description
N-[(S)-(2,3,4,5,6-Pentafluorophenoxy)phenoxyphosphinyl]-L-alanine 1-Methylethyl Ester is a reactant in the synthesis of phosphoramidate imidazo[2,1-f][1,2,4]triazine-4-amine adenosine prodrugs that can increase anti-HCV activity.More related product prices
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