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ChemicalBook > Product Catalogue >Pharmaceutical intermediates >Bulk Drug Intermediates >2'-deoxy-2'-fluoro-2'-C-methyluridine

2'-deoxy-2'-fluoro-2'-C-methyluridine

2'-deoxy-2'-fluoro-2'-C-methyluridine Structure
  • ₹5900 - ₹16500
  • Product name: 2'-deoxy-2'-fluoro-2'-C-methyluridine
  • CAS: 863329-66-2
  • MF: C10H13FN2O5
  • MW: 260.22
  • EINECS:810-481-6
  • MDL Number:MFCD19982668
  • Synonyms:2'-deoxy-2'-fluoro-2'-methyluridine;1-[(2R,3R,4R,5R)-3-Fluoro-4-hydroxy-5-(hydroxymethyl)-3-methyl-tetrahydrofuran-2-yl]pyrimidine-2,4-dione;2'-deoxy-2'-fluoro-2'-C-methyluridine;2'-Deoxy-2-floro-2'Methyl-uridine;1-((2S,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxyMethyl)-3-Methyltetrahydrofuran-2-yl)pyriMidine-2,4(1H,3H)-dione;1-((2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxyMethyl)-3-Methyltetrahydrofuran-2-yl)pyriMidine-2,4(1H,3H)-dione;PSI-6206;RO 2433
2 prices
Selected condition:

Brand

  • TCI Chemicals (India)

Package

  • 200MG
  • 1G
  • ManufacturerTCI Chemicals (India)
  • Product numberD4823
  • Product descriptionPSI-6206
  • Packaging1G
  • Price₹16500
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberD4823
  • Product descriptionPSI-6206
  • Packaging200MG
  • Price₹5900
  • Updated2022-05-26
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
TCI Chemicals (India) D4823 PSI-6206 1G ₹16500 2022-05-26 Buy
TCI Chemicals (India) D4823 PSI-6206 200MG ₹5900 2022-05-26 Buy

Properties

Melting point :237-238℃
Density :1.55
storage temp. :Sealed in dry,Store in freezer, under -20°C
solubility :DMSO (Slightly), Methanol (Slightly, Heated)
pka :9.39±0.10(Predicted)
form :Solid
color :White to Light Beige

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321 Specific treatment (see … on this label).
P330 Rinse mouth.
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P362 Take off contaminated clothing and wash before reuse.
P501 Dispose of contents/container to..…

Description

PSI-6206 is the deaminated derivative of PSI-6130, a selective inhibitor of hepatitis C virus (HCV) replication that targets the NS5B polymerase. PSI-6206, itself, does not inhibit HCV replication in the HCV subgenomic replicon assay. However, its triphosphate form, RO 2433-TP, does inhibit RNA synthesis by HCV polymerase (IC50 = 1.19 μM for inhibition of RNA synthesis activity of HCV replicase).

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