25 MG CALPAIN INHIBITOR IIRESEARCH GRADE
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- Product name: 25 MG CALPAIN INHIBITOR IIRESEARCH GRADE
- CAS: 136632-32-1
- MF: C19H35N3O4S1
- MW: 401.56
- EINECS:603-969-3
- MDL Number:MFCD00065506
- Synonyms:Calpain Inhibitor II, ALLM;CALPAIN INHIBITOR II (N-AC-LEU-LEU METHIORINAL);N-acetyl-Leu-Leu-methional;ALLM (Calpain Inhibitor) 95% purity;ALLM (Calpain Inhibitor);25 MG CALPAIN INHIBITOR IIRESEARCH GRADE;Calpain Inhibitor II powder;ALLM (Ac-Leu-Leu-Met-CHO)
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Properties
storage temp. :−20°C
solubility :Soluble in ethanol at 20mg/ml
form :powder
color :white
BRN :7693643
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.
solubility :Soluble in ethanol at 20mg/ml
form :powder
color :white
BRN :7693643
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.
Safety Information
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Description
ALLM (Calpain Inhibitor) is a cell-permeable, peptide aldehyde inhibitor of calpain I and calpain II. ALLM acts as a very potent inhibitor of cathepsin L and the strongest inhibitor of cathepsin B amongst the peptide aldehydes. This compound inhibits the processing of malaria aspartic hemoglobinases plasmepsins I and II?in vitro. ALLM also inhibits other neutral cysteine proteases, and activation-induced programmed cell death. It restores defective immune responses in HIV+ donors. ALLM blocks nitric oxide production by activated macrophages by interfering with transcription of the inducible nitric oxide synthase gene. ALLM also acts as a weak inhibitor of proteasome.Related product price
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