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MG-115

MG-115 Structure
  • ₹5596.53 - ₹21460
  • Product name: MG-115
  • CAS: 133407-86-0
  • MF: C25H39N3O5
  • MW: 461.59
  • EINECS:
  • MDL Number:MFCD00274411
  • Synonyms:PROTEASOME INHIBITOR MG-115;N-CBZ-LEU-LEU-NORVALINAL;MG-115;Z-LL-NVA-CHO;Z-LEU-LEU-NVA-ALDEHYDE;Z-LEU-LEU-NVA-CHO;Z-LEU-LEU-NVA-H;Z-LEU-LEU-NVA-H (ALDEHYDE)
3 prices
Selected condition:

Brand

  • Sigma-Aldrich(India)

Package

  • 1MG
  • 5MG
  • ManufacturerSigma-Aldrich(India)
  • Product numberC6706
  • Product descriptionZ-Leu-Leu-Norvalinal ≥90% (HPLC), powder
  • Packaging1MG
  • Price₹5596.53
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberC6706
  • Product descriptionZ-Leu-Leu-Norvalinal ≥90% (HPLC), powder
  • Packaging5MG
  • Price₹15566.35
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number474780
  • Product descriptionMG-115 - CAS 133407-86-0 - Calbiochem Potent reversible proteasome inhibitor (Ki = 21 nM and 35 nM for 20S and 26S proteasome, respectively).
  • Packaging5MG
  • Price₹21460
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) C6706 Z-Leu-Leu-Norvalinal ≥90% (HPLC), powder 1MG ₹5596.53 2022-06-14 Buy
Sigma-Aldrich(India) C6706 Z-Leu-Leu-Norvalinal ≥90% (HPLC), powder 5MG ₹15566.35 2022-06-14 Buy
Sigma-Aldrich(India) 474780 MG-115 - CAS 133407-86-0 - Calbiochem Potent reversible proteasome inhibitor (Ki = 21 nM and 35 nM for 20S and 26S proteasome, respectively). 5MG ₹21460 2022-06-14 Buy

Properties

Boiling point :678.8±55.0 °C(Predicted)
Density :1.082±0.06 g/cm3(Predicted)
storage temp. :-20°C
solubility :DMSO: soluble
form :powder
pka :11.14±0.46(Predicted)
color :white

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

(S)-MG115 is a potent and reversible proteasome inhibitor, targeting the chymotryptic site on the 20S particle (Ki = 21 nM). It reduces the degradation of ubiquitin-conjugated proteins in extracts. (S)-MG115 also blocks the degradation of long- and short-lived proteins in intact cells as well as the proteolytic generation of diverse proteins, including NF-κB, antigens, and p53. Proteasome inhibitors, including (S)-MG115, can induce a heat shock response and apoptosis, particularly in cancer cells.

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