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15(S)-Fluprostenol isopropyl ester

15(S)-Fluprostenol isopropyl ester Structure
  • ₹0
  • Product name: 15(S)-Fluprostenol isopropyl ester
  • CAS: 1420791-14-5
  • MF: C26H35F3O6
  • MW: 500.55
  • EINECS:
  • MDL Number:
  • Synonyms:DSDQWKRCNBYHOQ-BZQTUMIFSA-N;Travoprost Impurity 5（15-epi-Travoprost）;15S-Travoprost/15-epi-Travoprost/(5Z)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(1E,3S)-3-hydroxy-4-[3-(trifluoromethyl)phenoxy]-1-buten-1-yl]cyclopentyl]-5-heptenoic Acid 1-Methylethyl Ester;Travoprost 15-epi Diastereomer;5-Heptenoic acid, 7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(1E,3S)-3-hydroxy-4-[3-(trifluoromethyl)phenoxy]-1-buten-1-yl]cyclopentyl]-, 1-methylethyl ester, (5Z)-;Travoprost Impurity 32;(Z)-isopropyl7-((1R,2R,3R,5S)-3,5-dihydroxy-2-((S,E)-3-hydroxy-4-(3-(trifluoromethyl)phenoxy)but-1-en-1-yl)cyclopentyl)hept-5-enoate;isopropyl (5Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(1E,3S)-3-hydroxy-4-[3-(trifluoromethyl)-phenoxy]-1-butenyl]cyclopentyl]-5-heptenoate
Properties Safety Information Description
Manufacturer Product number Product description Packaging Price Updated Buy

Properties

Boiling point :584.8±50.0 °C(Predicted)
Density :1.245±0.06 g/cm3(Predicted)
solubility :DMF: 15 mg/ml; DMSO: 12 mg/ml; Ethanol: 30 mg/ml; Ethanol:PBS (pH 7.2) (1:1): 1 mg/ml
pka :13.43±0.20(Predicted)
form :Oil to Thick Oil
color :Colourless
Stability :Light Sensitive

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P330 Rinse mouth.
P501 Dispose of contents/container to..…

Description

15(S)-Fluprostenol isopropyl ester (15(S)-Flu-Ipr) is the unnatural C-15 epimer of Travoprost. Travoprost is the Alcon trade name for fluprostenol isopropyl ester, (Flu-Ipr) an F-series prostaglandin analog which has been approved for use as an ocular hypotensive drug. Flu-Ipr is a prodrug which is converted by esterase enzymatic activity in the cornea to yield the corresponding free acid. The free acid, fluprostenol, is a potent FP receptor agonist. In human and animal models of glaucoma, FP receptor agonist activity corresponds very closely with intraocular hypotensive activity. Although data is currently not available for the activity of 15(S)-Flu-Ipr, inversion of the stereochemistry at the 15 position of ocular hypotensive prostaglandins generally lowers the potency approximately 100 fold.

More related product prices

404830-45-1 5,6-trans Travoprost 5-TRANS FLUPROSTENOL cis-Atovaquone Travoprost Acid 9-KETO FLUPROSTENOL 1219032-18-4 3-Trifluoromethylphenol 15-KETO FLUPROSTENOL Travoprost Ethyl bromoacetate Iodoethane Isopropyl acetate

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Suppliers and manufacturers

GLP Pharma Standards CHEMAZON LABORATORIES CLEARSYNTH LABS LTD. SynZeal Research Pvt Ltd Pharmaffiliates Analytics and Synthetics P. Ltd
sgtlifesciences pvt ltd
China National Standard Pharmaceutical Corporation Limited Cayman Chemical Company Shanghai Yifei Biotechnology Co. , Ltd. TOSUN PHARM