15-Keto Travoprost
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- ₹0
- Product name: 15-Keto Travoprost
- CAS: 404830-45-1
- MF: C26H33F3O6
- MW: 498.53
- EINECS:
- MDL Number:MFCD02259342
- Synonyms:15-KETO TRAVOPROST;15-KETO FLUPROSTENOL ISOPROPYL ESTER;15-OXO-9ALPHA,11ALPHA-DIHYDROXY-16-(3-(TRIFLUOROMETHYL)PHENOXY)-17,18,19,20-TETRANOR-PROSTA-5Z,13E-DIEN-1-OIC ACID, ISOPROPYL ESTER;(5Z)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(1E)-3-oxo-4-[3-(trifluoroMethyl)phenoxy]-1-butenyl]cyclopentyl]-5-heptenoic Acid 1-Methylethyl Ester;5-Heptenoic acid, 7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(1E)-3-oxo-4-[3-(trifluoroMethyl)phe noxy]-1-butenyl]cyclopentyl]-, 1-Methylethyl ester, (5Z)-;(5Z)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(1E)-3-oxo-4-[3-(trifluoromethyl)phenoxy]-1-buten-1-yl]cyclopentyl]-5-heptenoic acid 1-methylethyl ester;15-keton-Travoprost;propan-2-yl (Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(E)-3-oxo-4-[3-(trifluoromethyl)phenoxy]but-1-enyl]cyclopentyl]hept-5-enoate
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Properties
Boiling point :577.5±50.0 °C(Predicted)
Density :1.242±0.06 g/cm3(Predicted)
storage temp. :Amber Vial, -20°C Freezer, Under inert atmosphere
solubility :Chloroform (Slightly), Methanol (Slightly)
form :Thick oil
form :Thick Oil
pka :14.38±0.70(Predicted)
color :Yellow to Brown
Stability :Light Sensitive
Density :1.242±0.06 g/cm3(Predicted)
storage temp. :Amber Vial, -20°C Freezer, Under inert atmosphere
solubility :Chloroform (Slightly), Methanol (Slightly)
form :Thick oil
form :Thick Oil
pka :14.38±0.70(Predicted)
color :Yellow to Brown
Stability :Light Sensitive
Safety Information
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Signal word: | Warning | ||||||||||||||
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Description
Travoprost is an F-series prostaglandin analog which has been approved for use as an ocular hypotensive drug. Oxidation of the C-15 hydroxyl group without isopropyl ester hydrolysis produces 15-keto fluprostenol isopropyl ester (15-keto travoprost). 15-keto Travoprost is a potential metabolite of travoprost when administered to intact animals. 15-keto Travoprost is also one of the common minor impurities found in commercial preparations of the bulk drug compound. In general, F-series prostaglandin analogs with a 15-keto functional group lose a great deal of their FP receptor binding affinity, but retain enough to show a continued weak IOP hypotensive response. The efficacy of 15-keto travoprost as an ocular hypotensive has not been established.More related product prices
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