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4'-Hydroxyphenyl Carvedilol

4'-Hydroxyphenyl Carvedilol Structure
  • ₹0
  • Product name: 4'-Hydroxyphenyl Carvedilol
  • CAS: 142227-49-4
  • MF: C24H26N2O5
  • MW: 422.47
  • EINECS:
  • MDL Number:MFCD04039561
  • Synonyms:(R)-(+)-4'-HYDROXYPHENYL-CARVEDILOL;(S)-(-)-4'-HYDROXYPHENYL-CARVEDILOL;(R)-4-[2-[[3-(9H-carbazol-4-yloxy)-2-hydroxypropyl]amino]ethoxy]-3-methoxyphenol;(R)-4-Hydroxycarvedilol;(R)-BM 140686;(R)-BM 14686;(S)-4-[2-[[3-(9H-carbazol-4-yloxy)-2-hydroxypropyl]amino]ethoxy]-3-methoxyphenol;(S)-4-Hydroxycarvedilol
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Properties

Melting point :163-165°C
Boiling point :702.0±60.0 °C(Predicted)
Density :1.305±0.06 g/cm3(Predicted)
storage temp. :-20°C Freezer
solubility :Acetonitrile (Slightly), DMSO (Slightly), Methanol (Slightly)
form :Solid
pka :9.94±0.20(Predicted)
color :White to Light Brown

Safety Information

Symbol(GHS):
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Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
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Description

4’-hydroxyphenyl Carvedilol is a metabolite of carvedilol that is a more potent β-adrenergic receptor antagonist than carvedilol but has weaker vasodilatory activity. It is formed through oxidation primarily by the cytochrome P450 (CYP) isoform CYP2D6. 4’-hydroxyphenyl Carvedilol inhibits the formation of DPPH radicals in a cell-free assay.

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