CAY10683 (SantacruzaMate A)
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- ₹0
- Product name: CAY10683 (SantacruzaMate A)
- CAS: 1477949-42-0
- MF: C15H22N2O3
- MW: 278.35
- EINECS:-0
- MDL Number:MFCD28348356
- Synonyms:CAY10683 (SantacruzaMate A);ETHYL 4-OXO-4-(PHENETHYLAMINO)BUTYLCARBAMATE;N-[4-oxo-4-[(2-phenylethyl)amino]butyl]-carbamic acid ethyl ester;CAY1083;Carbamic acid, N-[4-oxo-4-[(2-phenylethyl)amino]butyl]-, ethyl ester;Santacruzamate A, >98%;CAY 10683;CAY-10683;CS-1702
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Properties
Boiling point :508.1±43.0 °C(Predicted)
Density :1.087±0.06 g/cm3(Predicted)
storage temp. :-20°
solubility :Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 20 mg/ml).
form :solid
pka :12.68±0.46(Predicted)
color :Off-white
Stability :Stable for 2 years from date of purchse as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 2 months.
Density :1.087±0.06 g/cm3(Predicted)
storage temp. :-20°
solubility :Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 20 mg/ml).
form :solid
pka :12.68±0.46(Predicted)
color :Off-white
Stability :Stable for 2 years from date of purchse as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 2 months.
Safety Information
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Description
CAY10683 is a potent histone deacetylase (HDAC) inhibitor isolated from the cyanobacterium Symploca. It inhibits HDAC2 and HDAC6 with IC50 values of 0.119 and 434 nM, respectively, and is without effect against HDAC4 (IC50 = >1,000 nM). CAY10683 inhibits the growth of HCT-116 colon cancer cells and HuT-78 cutaneous T cell lymphoma cells (GI50 = 29.4 and 1.4 μM, respectively) more effectively than human dermal fibroblasts (GI50 = >100 μM).More related product prices
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