1,3,5[10]-ESTRATRIENE-3,17BETA-DIOL 17-GLUCURONIDE SODIUM SALT
- ₹10030 - ₹79620
- Product name: 1,3,5[10]-ESTRATRIENE-3,17BETA-DIOL 17-GLUCURONIDE SODIUM SALT
- CAS: 15087-02-2
- MF: C24H31NaO8
- MW: 470.49
- EINECS:
- MDL Number:MFCD00056557
- Synonyms:1,3,5(10)-ESTRATRIEN-3,17-BETA-DIOL 17-GLUCOSIDURONATE SODIUM SALT;1,3,5[10]-ESTRATRIENE-3,17BETA-DIOL 17-GLUCURONIDE SODIUM SALT;BETA-ESTRADIOL 17-(BETA-D-GLUCURONIDE) SODIUM SALT;oestradiol 17-(beta-D-glucuronide), sodium salt;1,3,5(10)-Estratriene-3,17β-diol 17-glucuronide, 3,17β-Dihydroxy-1,3,5(10)-estratriene 17-glucuronide;β-Estradiol 17-(β-D-glucuronide) sodium salt;1,3,5(10)-Estratriene-3,17β-diol 17-glucuronide;3,17β-Dihydroxy-1,3,5(10)-estratriene 17-glucuronide
4 prices
Selected condition:
Brand
- Sigma-Aldrich(India)
Package
- 5MG
- 10MG
- 25MG
- 100MG
- ManufacturerSigma-Aldrich(India)
- Product numberE1127
- Product descriptionβ-Estradiol 17-(β-D-glucuronide) sodium salt
- Packaging5MG
- Price₹10030
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberE1127
- Product descriptionβ-Estradiol 17-(β-D-glucuronide) sodium salt
- Packaging10MG
- Price₹16400
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberE1127
- Product descriptionβ-Estradiol 17-(β-D-glucuronide) sodium salt
- Packaging25MG
- Price₹29680
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberE1127
- Product descriptionβ-Estradiol 17-(β-D-glucuronide) sodium salt
- Packaging100MG
- Price₹79620
- Updated2022-06-14
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
Sigma-Aldrich(India) | E1127 | β-Estradiol 17-(β-D-glucuronide) sodium salt | 5MG | ₹10030 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | E1127 | β-Estradiol 17-(β-D-glucuronide) sodium salt | 10MG | ₹16400 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | E1127 | β-Estradiol 17-(β-D-glucuronide) sodium salt | 25MG | ₹29680 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | E1127 | β-Estradiol 17-(β-D-glucuronide) sodium salt | 100MG | ₹79620 | 2022-06-14 | Buy |
Properties
Melting point :>245°C (dec.)
storage temp. :−20°C
solubility :DMSO (Slightly), Ethanol (Slightly, Heated, Sonicated), Methanol (Slightly)
form :Solid
color :White to Off-White
Stability :Hygroscopic
storage temp. :−20°C
solubility :DMSO (Slightly), Ethanol (Slightly, Heated, Sonicated), Methanol (Slightly)
form :Solid
color :White to Off-White
Stability :Hygroscopic
Safety Information
Symbol(GHS): | |||||||||||||||
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Signal word: | Warning | ||||||||||||||
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Description
Estradiol 17-(β-D-glucuronide) (E217G) is an estrogen metabolite formed in the liver and subsequently excreted in bile. It acts as a substrate of the multidrug resistance protein 2 (MRP2; Km = 75 μM), and through MRP2-mediated transport, functions as a cholestatic agent, decreasing bile flow. In addition to binding to the MRP2 transport site, E217G has been shown to bind to an allosteric site that through positive cooperativity activates its own transport via MRP2 and the transport of other MRP2 substrates, including the non-cholestatic estrogen metabolite, estradiol 3-(β-D-glucuronide) (E23G; ). E217G has also been reported to be transported by MDR1, MRP1, MRP3, MRP4, MRP7, ABCG2 (a breast cancer resistance protein transporter), and the rat organic anion-transporting polypeptides 1-4.More related product prices
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