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ChemicalBook > Product Catalogue >Pharmaceutical intermediates >Heterocyclic compound >Pyrimidines >Iodine pyrimidine >3-Iodo-1H-pyrazolo[3,4-d]pyrimidin-4-amine

3-Iodo-1H-pyrazolo[3,4-d]pyrimidin-4-amine

3-Iodo-1H-pyrazolo[3,4-d]pyrimidin-4-amine  Structure
  • ₹8800 - ₹15200
  • Product name: 3-Iodo-1H-pyrazolo[3,4-d]pyrimidin-4-amine
  • CAS: 151266-23-8
  • MF: C5H4IN5
  • MW: 261.02
  • EINECS:
  • MDL Number:MFCD03787931
  • Synonyms:3-iodo-2H-pyrazolo[3,4-d]pyrimidin-4-amine;3-IODO-1H-PYRAZOLO[3,4-D]PYRIMIDIN-4-YLAMINE;4-AMINO-3-IODO-1H-PYRAZOLO[3,4-D]PYRIMIDINE;1H-Pyrazolo[3,4-d]pyrimidin-4-amine, 3-iodo-;4-Amino-3-iodo-1H-pyrazolo[3,4-D]pyridine;3-iodo-4-AMino-1H-pyrazolo[3,4-d]pyridine;7-Iodo-7-deaza-8-aza-adenine;3-iodopyrazolo[3,4-d]pyriMidin-4-aMine
2 prices
Selected condition:

Brand

  • TCI Chemicals (India)

Package

  • 1G
  • 5G
  • ManufacturerTCI Chemicals (India)
  • Product numberI0941
  • Product description3-Iodo-1H-pyrazolo[3,4-d]pyrimidin-4-amine
  • Packaging1G
  • Price₹8800
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberI0941
  • Product description3-Iodo-1H-pyrazolo[3,4-d]pyrimidin-4-amine
  • Packaging5G
  • Price₹15200
  • Updated2022-05-26
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
TCI Chemicals (India) I0941 3-Iodo-1H-pyrazolo[3,4-d]pyrimidin-4-amine 1G ₹8800 2022-05-26 Buy
TCI Chemicals (India) I0941 3-Iodo-1H-pyrazolo[3,4-d]pyrimidin-4-amine 5G ₹15200 2022-05-26 Buy

Properties

Boiling point :312.3±52.0 °C(Predicted)
Density :2.92±0.1 g/cm3(Predicted)
storage temp. :Keep in dark place,Sealed in dry,Room Temperature
form :powder to crystal
pka :10.50±0.20(Predicted)
color :White to Light yellow to Light orange
Sensitive :Light Sensitive
λmax :282nm(lit.)
InChI :InChI=1S/C5H4IN5/c6-3-2-4(7)8-1-9-5(2)11-10-3/h1H,(H3,7,8,9,10,11)
InChIKey :HQAIUXZORKJOJY-UHFFFAOYSA-N
SMILES :C1=NC(N)=C2C(I)=NNC2=N1

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405 Store locked up.

Description

3-Iodo-3H-pyrazolo[3,4-d]pyrimidin-4-amine acts as a reagent in the discovery and preparation of CHMFL-FLT3-122 as potent and orally available FLT3 kinase inhibitor for FLT3-ITD positive acute myeloid leukemia. Development and preparation of potent and selective Plasmodium falciparum calcium-dependent protein kinase 4 (PfCDPK4) inhibitors that block the transmission of malaria to mosquitoes.

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