4-(7,8,9,10-TETRAHYDRO-5,7,7,10,10-PENTAMETHYL-5H-BENZO[E]NAPHTHO[2,3-B][1,4]DIAZEPIN-13-YL)BENZOIC ACID
- ₹11463.68 - ₹46558.33
- Product name: 4-(7,8,9,10-TETRAHYDRO-5,7,7,10,10-PENTAMETHYL-5H-BENZO[E]NAPHTHO[2,3-B][1,4]DIAZEPIN-13-YL)BENZOIC ACID
- CAS: 155877-83-1
- MF: C29H30N2O2
- MW: 438.56
- EINECS:
- MDL Number:MFCD06798318
- Synonyms:4-(7,8,9,10-TETRAHYDRO-5,7,7,10,10-PENTAMETHYL-5H-BENZO[E]NAPHTHO[2,3-B][1,4]DIAZEPIN-13-YL)BENZOIC ACID;LE 135;4-(7,8,9,10-Tetrahydro-5,7,7,10,10-pentamethyl-(5H)-benzo[e]naphtho[2.3-b][1.4]diazepine-13-yl)benzoicacid;Benzoic acid, 4-(7,8,9,10-tetrahydro-5,7,7,10,10-pentaMethyl-5H-benzo[e]naphtho[2,3-b][1,4]diazepin-13-yl)-;4-(5,7,7,10,10-Pentamethyl-7,8,9,10-tetrahydro-5H-benzo[e]naphtho[2,3-b][1,4]diazepin-13-yl)benzoic acid;4-(7,8,9,10-Tetrahydro-5,7,7,10,10-pentamethyl-5H-benzo[e]naphtho[2,3-b][1,4]diazepin-13-yl)benzoic acid
2 prices
Selected condition:
Brand
- Sigma-Aldrich(India)
Package
- 5MG
- 25MG
- ManufacturerSigma-Aldrich(India)
- Product numberSML0809
- Product descriptionLE 135 ≥98% (HPLC)
- Packaging5MG
- Price₹11463.68
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberSML0809
- Product descriptionLE 135 ≥98% (HPLC)
- Packaging25MG
- Price₹46558.33
- Updated2022-06-14
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
Sigma-Aldrich(India) | SML0809 | LE 135 ≥98% (HPLC) | 5MG | ₹11463.68 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | SML0809 | LE 135 ≥98% (HPLC) | 25MG | ₹46558.33 | 2022-06-14 | Buy |
Properties
Boiling point :601.3±55.0 °C(Predicted)
Density :1.17±0.1 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: soluble15mg/mL, clear
pka :3.02±0.10(Predicted)
form :powder
color :yellow to orange
Density :1.17±0.1 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: soluble15mg/mL, clear
pka :3.02±0.10(Predicted)
form :powder
color :yellow to orange
Safety Information
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Signal word: | Warning | |||||||||||||||||||||
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Description
LE 135 is a retinoic acid receptor (RAR) antagonist that displays moderate selectivity for RARβ over RARα (Kis = 0.22 and 1.4 μM, respectively). LE 135 inhibits retinoic acid-induced transcriptional activation of RARβ (>70% inhibition at 10 μM), but not RARα, RARγ or retinoid X receptor α. It has been shown to inhibit retinoid Am80-induced differentiation of human promyelocytic leukemia cells, HL-60, with an IC50 value of 0.2 μM.Related product price
- 4-(TERT-BUTYL)-1,2-DIAMINOBENZENE
₹2147-13427 - 155877-83-1
₹11463.68-46558.33
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