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ChemicalBook > Product Catalogue >Biochemical Engineering >Amino Acids and Derivatives >Leucine derivatives >6-DIAZO-5-OXO-L-NORLEUCINE

6-DIAZO-5-OXO-L-NORLEUCINE

6-DIAZO-5-OXO-L-NORLEUCINE Structure
  • ₹5607.35 - ₹17157.63
  • Product name: 6-DIAZO-5-OXO-L-NORLEUCINE
  • CAS: 157-03-9
  • MF: C6H9N3O3
  • MW: 171.15
  • EINECS:251-228-4
  • MDL Number:MFCD00037218
  • Synonyms:6-diazo-5-oxo,l-norleucin ;6-diazo-5-oxo-l-norleucin ;diazo-oxo-norleucine ;don(pharmaceutical) ;6-DIAZO-5-OXO-L-2-AMINOHEXANOIC ACID;6-DIAZO-5-OXO-L-NORLEUCINE;6-DIAZO-5-OXO-NORLEUCINE;H-6-DIAZO-5-OXO-L-NORLEUCINE
2 prices
Selected condition:

Brand

  • Sigma-Aldrich(India)

Package

  • 5MG
  • 25MG
  • ManufacturerSigma-Aldrich(India)
  • Product numberD2141
  • Product description6-Diazo-5-oxo-L-norleucine crystalline
  • Packaging5MG
  • Price₹5607.35
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberD2141
  • Product description6-Diazo-5-oxo-L-norleucine crystalline
  • Packaging25MG
  • Price₹17157.63
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) D2141 6-Diazo-5-oxo-L-norleucine crystalline 5MG ₹5607.35 2022-06-14 Buy
Sigma-Aldrich(India) D2141 6-Diazo-5-oxo-L-norleucine crystalline 25MG ₹17157.63 2022-06-14 Buy

Properties

Melting point :145 °C
Boiling point :301.12°C (rough estimate)
Density :1.3994 (rough estimate)
refractive index :1.5800 (estimate)
storage temp. :-20°C
solubility :DMSO (Slightly, Heated, Sonicated), Water (Slightly)
form :crystalline
color :light yellow
Merck :13,3026
BRN :1725815
Stability :Hygroscopic

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

Description

6-Diazo-5-oxo-L-nor-Leucine (DON) is a glutamine analog that inhibits glutaminases (Ki = 6 μM) and other glutamine-utilizing enzymes, including cytidine triphosphate synthase (CTPS), which uses glutamine in the synthesis of CTP. DON is commonly used in cells or tissues but its use in whole animals is limited by its teratogenicity.

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