Sitafloxacin Sesquihydrate
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- Product name: Sitafloxacin Sesquihydrate
- CAS: 163253-35-8
- MF: C19H20ClF2N3O4
- MW: 427.83
- EINECS:1308068-626-2
- MDL Number:
- Synonyms:Sitafloxacin Sesquihydrate;7-[(7S)-7-Amino-5-azaspiro[2.4]heptan-5-yl]-8-chloro-6-fluoro-1-[(1R,2S)-2-fluorocyclopropyl]-1,4-dihydro-4-oxoquinoline-3-carboxylic acid hydrate (2:3);Sitafloxacin;3-Quinolinecarboxylic acid, 7-((7S)-7-amino-5-azaspiro(24)hept-5-yl)-8-chloro-6-fluoro-1-((1R,2S)-2-fluorocyclopropyl)-1,4-dihydro-4-oxo-, hydrate (2:3);3-Quinolinecarboxylic acid, 7-(7-amino-5-azaspiro(24)hept-5-yl)-8-chloro-6-fluoro-1-(2-fluorocyclopropyl)-1,4-dihydro-4-oxo-, hydrate (2:3), (1R-(1alpha(S*),2alpha))-;Du 6859a;Unii-9td681796g;Sitafloxacin hydrate (2:3)
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Properties
Melting point :145-147°C (dec.)
alpha :589 -199.9°
storage temp. :Keep in dark place,Sealed in dry,Store in freezer, under -20°C
solubility :Aqueous Base (Slightly), DMSO (Slightly), Methanol (Very Slightly, Heated)
form :Solid
color :White to Off-White
Stability :Hygroscopic
InChIKey :ANCJYRJLOUSQBW-UWQPBFEBNA-N
SMILES :N[C@@H]1CN(C2=C(C=C3C(=O)C(C(=O)O)=CN([C@@H]4C[C@@H]4F)C3=C2Cl)F)CC21CC2.O |&1:1,16,18,r|
CAS DataBase Reference :163253-35-8(CAS DataBase Reference)
alpha :589 -199.9°
storage temp. :Keep in dark place,Sealed in dry,Store in freezer, under -20°C
solubility :Aqueous Base (Slightly), DMSO (Slightly), Methanol (Very Slightly, Heated)
form :Solid
color :White to Off-White
Stability :Hygroscopic
InChIKey :ANCJYRJLOUSQBW-UWQPBFEBNA-N
SMILES :N[C@@H]1CN(C2=C(C=C3C(=O)C(C(=O)O)=CN([C@@H]4C[C@@H]4F)C3=C2Cl)F)CC21CC2.O |&1:1,16,18,r|
CAS DataBase Reference :163253-35-8(CAS DataBase Reference)
Safety Information
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Description
The fluoroquinolone antibacterial agent sitafloxacin hydrate was developed by Daiichi Sankyo and was approved and launched last year in Japan. Sitafloxacin’s mode of action is through inhibition of DNA gyrase and topoisomerase IV. It is indicated for the treatment of inflammatory infections such as laryngopharyngitis, adenoiditis, acute bronchitis, pneumonia, secondary infections due to chronic respiratory lesions, cystitis, pyelonephritis, urethritis, cervicitis, otitismedia, sinusitis, periodontitis, and pericoronitis and jaw inflammation. Due to its broad spectrum of potent antibacterial activity, sitafloxacin is expected to be clinically effective in treating severe cases of bacterial infection, relapse/recrudescence of infection and infections in which resistant bacteria are suspected to be the cause.Related product price
- 6480-68-8
₹3000-80873.58
