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PHENOL,2,2'-SULFONYLBIS[3,4,6-TRICHLORO]-

PHENOL,2,2'-SULFONYLBIS[3,4,6-TRICHLORO]- Structure
  • ₹12297.2 - ₹19050
  • Product name: PHENOL,2,2'-SULFONYLBIS[3,4,6-TRICHLORO]-
  • CAS: 1638-41-1
  • MF: C12H4Cl6O4S
  • MW: 456.94
  • EINECS:
  • MDL Number:MFCD00397032
  • Synonyms:PHENOL,2,2'-SULFONYLBIS[3,4,6-TRICHLORO]-;2,2'-Sulfonylbis(3,4,6-trichlorophenol);p38 MAP Kinase Inhibitor IV;p38 MAPK Inhibitor IV;p38 MAP Kinase Inhibitor IV - CAS 1638-41-1 - Calbiochem;Phenol, 3,4,6-trichloro-2-[(2,3,5-trichloro-6-hydroxyphenyl)sulfonyl]-;p38 MAP Kinase Inhibitor IV (B10);p38 MAP Kinase Inhibitor IV,p-38 MAP Kinase Inhibitor IV
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Brand

  • Sigma-Aldrich(India)

Package

  • 5MG
  • 10MG
  • ManufacturerSigma-Aldrich(India)
  • Product numberSML0543
  • Product descriptionp38 MAP Kinase Inhibitor IV ≥98% (HPLC)
  • Packaging5MG
  • Price₹12297.2
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number506153
  • Product descriptionp38 MAP Kinase Inhibitor IV - CAS 1638-41-1 - Calbiochem The p38 MAP Kinase Inhibitor IV, also referenced under CAS 1638-41-1, controls the biological activity of p38 MAP Kinase. This small molecule/inhibito
  • Packaging10MG
  • Price₹19050
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) SML0543 p38 MAP Kinase Inhibitor IV ≥98% (HPLC) 5MG ₹12297.2 2022-06-14 Buy
Sigma-Aldrich(India) 506153 p38 MAP Kinase Inhibitor IV - CAS 1638-41-1 - Calbiochem The p38 MAP Kinase Inhibitor IV, also referenced under CAS 1638-41-1, controls the biological activity of p38 MAP Kinase. This small molecule/inhibito 10MG ₹19050 2022-06-14 Buy

Properties

Melting point :244-245 °C(Solv: ethyl acetate (141-78-6))
Boiling point :590.0±50.0 °C(Predicted)
Density :1.854±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: soluble5mg/mL, clear (warmed)
form :powder
pka :2.43±0.50(Predicted)
color :white to beige

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
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Description

p38 MAP Kinase Inhibitor IV is a cell permeable sulfone compound which functions as an ATP-competitive inhibitor of p38α and p38β MAP Kinases. In addition, p38 MAP Kinase Inhibitor IV inhibits p38&gamma/δ, ERK1/2, and JNK1/2/3 to a lesser extent. Furthermore, studies indicate that p38 MAP Kinase Inhibitor IV suppresses LPS-induced IL-1&beta release from hPBMC more effectively than SB 203850. Since MAP Kinases are responsible for signal transduction in cascade controlling cellular responses the inhibitor can possibly be used to inhibit apoptosis and other responses to stress stimuli.

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