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ChemicalBook > Product Catalogue >Organic Chemistry >Amides >Amides >4-(2-(5-Chloro-2-methoxybenzamido)ethyl)benzenesulfamide

4-(2-(5-Chloro-2-methoxybenzamido)ethyl)benzenesulfamide

4-(2-(5-Chloro-2-methoxybenzamido)ethyl)benzenesulfamide Structure
  • ₹3150.08 - ₹45529.95
  • Product name: 4-(2-(5-Chloro-2-methoxybenzamido)ethyl)benzenesulfamide
  • CAS: 16673-34-0
  • MF: C16H17ClN2O4S
  • MW: 368.84
  • EINECS:240-722-5
  • MDL Number:MFCD00193756
  • Synonyms:4-(2-(5-Chloro-2-methoxybenzamido)ethyl)benzenesulfamide ;Glyburide Related Compound A (25 mg) (5-chloro-2-methoxy-N-[2-(4-sulfamoylphenyl)ethyl]benzamide);4-[2-(2-Methoxy-5-chlorobenzene-1-carboxaMido)ethyl]benzenesulfonaMide;5-Chloro-N-(p-sulfaMoylphenethyl)-o-anisaMide;GlibenclaMide (Glyburide) IMpurity A;Glyburide Related CoMpound A;Glyburide Related Compound A (25 mg) (4-[2-(5-chloro-2-methoxybenzamido)ethyl]benzenesulfonamide);Glyburide USP RC A
2 prices
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Brand

  • Sigma-Aldrich(India)

Package

  • 50MG
  • 5G
  • ManufacturerSigma-Aldrich(India)
  • Product number463442
  • Product description5-Chloro-2-methoxy-N-[2-(4-sulfamoylphenyl)ethyl]benzamide 95%
  • Packaging5G
  • Price₹3150.08
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberPHR2414
  • Product descriptionGlyburide Related Compound A Pharmaceutical Secondary Standard; Certified Reference Material
  • Packaging50MG
  • Price₹45529.95
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) 463442 5-Chloro-2-methoxy-N-[2-(4-sulfamoylphenyl)ethyl]benzamide 95% 5G ₹3150.08 2022-06-14 Buy
Sigma-Aldrich(India) PHR2414 Glyburide Related Compound A Pharmaceutical Secondary Standard; Certified Reference Material 50MG ₹45529.95 2022-06-14 Buy

Properties

Melting point :209-214 °C
Density :1.356±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :Soluble in DMSO (up to 45 mg/ml).
form :Solid
pka :10.14±0.10(Predicted)
color :White
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.
CAS DataBase Reference :16673-34-0(CAS DataBase Reference)

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
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Description

NLRP3i (16673-34-0) is an NLRP3 inflammasome inhibitor which likely acts via interfering with the formation of the NLRP3 inflammasome complex and which exhibits promising?in vivo?protective activities in mouse acute myocardial infarction models. It blocks ASC aggregation, blocks the release of IL-1β and the activation of caspase-1 in macrophages expressing constitutively active NLRP3 but does not directly inhibit caspase-1.1,2?Limits infarct size after myocardial ischemia-reperfusion as well as leukocyte infiltration in a peritonitis model in mice.2

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