Welcome to chemicalbook!
400-158-6606
Try our best to find the right business for you.
Do not miss inquiry messages Please log in to view all inquiry messages.

Welcome back!

ChemicalBook > Product Catalogue >API >Hormones and the Endocrine System >Pancreatic hormone and blood sugar regulation >Glibenclamide

Glibenclamide

Glibenclamide Structure
  • ₹2100 - ₹20830
  • Product name: Glibenclamide
  • CAS: 10238-21-8
  • MF: C23H28ClN3O5S
  • MW: 494
  • EINECS:233-570-6
  • MDL Number:MFCD00056625
  • Synonyms:LABOTEST-BB LT00244861;GLIBENCLAMIDE;GLYBURIDE USP;GlibenclamideGlibenclamideBp;5-CHLORO-N-[4-(CYCLOHEXYLUREIDOSULFONYL)PHENETHYL]-2-METHOXYBENZAMIDE;5-CHLORO-N-[2-[4-[[[(CYCLOHEXYLAMINO)CARBONYL]AMINO]-SULFONYL]PHENYL]ETHYL]-2-METHOXYBENZAMIDE;adiab ;azuglucon
8 prices
Selected condition:

Brand

  • TCI Chemicals (India)
  • Sigma-Aldrich(India)

Package

  • 1G
  • 5G
  • 10G
  • 25G
  • ManufacturerTCI Chemicals (India)
  • Product numberG0382
  • Product descriptionGlibenclamide
  • Packaging5G
  • Price₹2100
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberG0382
  • Product descriptionGlibenclamide
  • Packaging25G
  • Price₹5600
  • Updated2022-05-26
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberPHR1287
  • Product descriptionGlyburide (Glibenclamide) Pharmaceutical Secondary Standard; Certified Reference Material
  • Packaging1G
  • Price₹8107.93
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number356310
  • Product descriptionGlyburide - CAS 10238-21-8 - Calbiochem A sulfonylurea that selectively blocks ATP-sensitive K+ channels.
  • Packaging1G
  • Price₹9380
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberG0639
  • Product descriptionGlybenclamide ≥99% (HPLC)
  • Packaging5G
  • Price₹10987.38
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberG2539
  • Product descriptionGlyburide meets USP testing specifications
  • Packaging5G
  • Price₹14906.03
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberG2539
  • Product descriptionGlyburide meets USP testing specifications
  • Packaging10G
  • Price₹16172.55
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberG0639
  • Product descriptionGlybenclamide ≥99% (HPLC)
  • Packaging10G
  • Price₹20830
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
TCI Chemicals (India) G0382 Glibenclamide 5G ₹2100 2022-05-26 Buy
TCI Chemicals (India) G0382 Glibenclamide 25G ₹5600 2022-05-26 Buy
Sigma-Aldrich(India) PHR1287 Glyburide (Glibenclamide) Pharmaceutical Secondary Standard; Certified Reference Material 1G ₹8107.93 2022-06-14 Buy
Sigma-Aldrich(India) 356310 Glyburide - CAS 10238-21-8 - Calbiochem A sulfonylurea that selectively blocks ATP-sensitive K+ channels. 1G ₹9380 2022-06-14 Buy
Sigma-Aldrich(India) G0639 Glybenclamide ≥99% (HPLC) 5G ₹10987.38 2022-06-14 Buy
Sigma-Aldrich(India) G2539 Glyburide meets USP testing specifications 5G ₹14906.03 2022-06-14 Buy
Sigma-Aldrich(India) G2539 Glyburide meets USP testing specifications 10G ₹16172.55 2022-06-14 Buy
Sigma-Aldrich(India) G0639 Glybenclamide ≥99% (HPLC) 10G ₹20830 2022-06-14 Buy

Properties

Melting point :173-175°C
Density :1.1805 (rough estimate)
refractive index :1.6100 (estimate)
storage temp. :2-8°C
solubility :ethanol: soluble2mg/mL
form :White solid
pka :5.3(at 25℃)
color :White
Water Solubility :Soluble in ethanol (5 mg/mL), DMSO (25 mg/mL), chloroform (1:36), methanol (1:250), and DMF. Insoluble in water.
Merck :14,4478
BCS Class :2
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
InChIKey :ZNNLBTZKUZBEKO-UHFFFAOYSA-N
CAS DataBase Reference :10238-21-8(CAS DataBase Reference)
NIST Chemistry Reference :Glyburide(10238-21-8)
EPA Substance Registry System :Benzamide, 5-chloro-N-[2-[4-[[[(cyclohexylamino)carbonyl]amino]sulfonyl]phenyl]ethyl]-2-methoxy- (10238-21-8)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H370 Causes damage to organs Specific target organ toxicity, single exposure Category 1 Danger GHS hazard pictograms P260, P264, P270, P307+P311, P321,P405, P501
Precautionary statements:
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

Glyburide (Glibenclamide) is a sulfonylurea compound that modulates insulin production. Sulfonylureas bind to ATP-dependent K+ channels in beta cells of the pancreas, depolarizing them and stimulating the release of Ca2+, which in turn stimulates insulin production. Glyburide (Glibenclamide) is an ATP-dependent K+ channel (KIR6, KATP) and CFTR Cl- channel blocker. This compound inhibits recombinant CFTR Cl- channels (IC50 = 20 ?M).

Related product price