1H-INDOLE-5-CARBOXAMIDE, 97%
|
- ₹15469.99
- Product name: 1H-INDOLE-5-CARBOXAMIDE, 97%
- CAS: 1670-87-7
- MF: C9H8N2O
- MW: 160.17
- EINECS:
- MDL Number:MFCD07779486
- Synonyms:1H-INDOLE-5-CARBOXAMIDE, 97%;SD-169;1H-Indole-5-carboxamide(9CI);5-(AMinocarbonyl)-1H-indole;5-CarbaMoylindole;p38 MAP Kinase Inhibitor VII, SD-169 ;5-(Aminocarbonyl)-1H-indole, 5-Carbamoylindole, 5-Carboxamidoindole;p38 MAP Kinase Inhibitor VII, SD-169 - CAS 1670-87-7 - Calbiochem
1 prices
Selected condition：
Brand
- Sigma-Aldrich(India)
Package
- 10MG
- ManufacturerSigma-Aldrich(India)
- Product number506158
- Product descriptionp38 MAP Kinase Inhibitor VII, SD-169 - CAS 1670-87-7 - Calbiochem The p38 MAP Kinase Inhibitor VII, SD-169, also referenced under CAS 1670-87-7, controls the biological activity of p38 MAP Kinase.
- Packaging10MG
- Price₹15469.99
- Updated2022-06-14
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | 506158 | p38 MAP Kinase Inhibitor VII, SD-169 - CAS 1670-87-7 - Calbiochem The p38 MAP Kinase Inhibitor VII, SD-169, also referenced under CAS 1670-87-7, controls the biological activity of p38 MAP Kinase. | 10MG | ₹15469.99 | 2022-06-14 | Buy |
Properties
Melting point :159-163 °C
Boiling point :457.6±18.0 °C(Predicted)
Density :1.328±0.06 g/cm3(Predicted)
storage temp. :Sealed in dry,2-8°C
solubility :DMSO (Slightly), Methanol (Slightly)
pka :16.25±0.30(Predicted)
form :Off-white solid
color :Off-White to Light Purple
Boiling point :457.6±18.0 °C(Predicted)
Density :1.328±0.06 g/cm3(Predicted)
storage temp. :Sealed in dry,2-8°C
solubility :DMSO (Slightly), Methanol (Slightly)
pka :16.25±0.30(Predicted)
form :Off-white solid
color :Off-White to Light Purple
Safety Information
| Symbol(GHS): |
|
|||||||||||||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Signal word: | Warning | |||||||||||||||||||||||||||||||||||
| Hazard statements: |
|
|||||||||||||||||||||||||||||||||||
| Precautionary statements: |
|
Description
SD 169 is a selective ATP competitive inhibitor of the MAP kinases p38α (IC50 = 3.2 nM) and p38β (IC50 = 122 nM). It has no inhibitory effect against a panel of other kinases, including p38γ MAP kinase, ERK2, JNK-1, and MAPKAPK-2, when tested in vitro at 50 μM. SD 169 is orally active, significantly reducing p38 MAP kinase expression in T cells of nonobese diabetic mice when delivered in chow at 600 mg/kg. In this model, SD 169 also reduced the incidence of diabetes, lowered blood glucose, and improved glucose homeostasis. SD 169 also enhances axonal regeneration after sciatic nerve crush injury in rats, when given by gavage (30 mg/kg) before and after nerve damage.More related product prices
SD-208