2-AG
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- ₹29738.8
- Product name: 2-AG
- CAS: 53847-30-6
- MF: C23H38O4
- MW: 378.55
- EINECS:200-835-2
- MDL Number:MFCD01862600
- Synonyms:5Z,8Z,11Z,14Z-EICOSATETRAENOIC ACID, 2-GLYCERYL ESTER;(5Z,8Z,11Z,14Z)-5,8,11,14-EICOSATETRAENOIC ACID, 2-HYDROXY-1-(HYDROXYMETHYL)ETHYL ESTER;2-AG;NOLADIN;(5Z,8Z,11Z,14Z)-5,8,11,14-Eicosatetraenoicacid;2-Hydroxy-1-(hydroxymethyl)ethylester;1,3-dihydroxypropan-2-yl (5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoate;2-Ara-gl
1 prices
Selected condition：
Brand
- Sigma-Aldrich(India)
Package
- 5MG
- ManufacturerSigma-Aldrich(India)
- Product numberA8973
- Product description2-Arachidonyl glycerol ~10?mg/mL, ≥98% (HPLC)
- Packaging5MG
- Price₹29738.8
- Updated2022-06-14
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | A8973 | 2-Arachidonyl glycerol ~10?mg/mL, ≥98% (HPLC) | 5MG | ₹29738.8 | 2022-06-14 | Buy |
Properties
Boiling point :508.6±50.0 °C(Predicted)
Density :0.992±0.06 g/cm3(Predicted)
Flash point :2 °C
storage temp. :-20°C
solubility :DMSO: 10 mg/ml; Ethanol: Miscible; PBS (pH 7.2): ~150 μg/ml
form :acetonitrile solution
pka :13.54±0.10(Predicted)
color :Colorless to light yellow
CAS DataBase Reference :53847-30-6(CAS DataBase Reference)
Density :0.992±0.06 g/cm3(Predicted)
Flash point :2 °C
storage temp. :-20°C
solubility :DMSO: 10 mg/ml; Ethanol: Miscible; PBS (pH 7.2): ~150 μg/ml
form :acetonitrile solution
pka :13.54±0.10(Predicted)
color :Colorless to light yellow
CAS DataBase Reference :53847-30-6(CAS DataBase Reference)
Safety Information
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| Signal word: | Danger | |||||||||||||||||||||
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Description
2-Arachidonoyl glycerol (2-AG) is an endogenous agonist of the CB1 and CB2 receptors (Kis = 58 and 145 nM, respectively). Unlike anandamide, 2-AG is present at relatively high levels in the central nervous system; it is the most abundant molecular species of monoacylglycerol found in rat brain. Formation of 2-AG is calcium-dependent and is mediated by the activities of PLC and DAG lipase. 2-AG acts as a full agonist at the CB1 receptor. At a concentration of 0.3 nM, 2-AG induces a rapid, transient increase in intracellular free calcium in NG108-15 neuroblastoma X glioma cells through a CB1 receptor-dependent mechanism. 2-AG is metabolized in vitro by MAG lipase and fatty acid amide hydrolase, with MAG lipase likely being the principle metabolizing enzyme in vivo.Related product price
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