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20-CARBOXY-LEUKOTRIENE B4

20-CARBOXY-LEUKOTRIENE B4 Structure
  • ₹33290
  • Product name: 20-CARBOXY-LEUKOTRIENE B4
  • CAS: 80434-82-8
  • MF: C20H30O6
  • MW: 366.45
  • EINECS:
  • MDL Number:MFCD00065857
  • Synonyms:20-CARBOXY-LEUKOTRIENE B4;20-COOH-LTB4;5S,12R-DIHYDROXY-6Z,8E,10E,14Z-EICOSATETRAENE-1,20-DIOIC ACID;(5S,6Z,8E,10E,12R,14Z)-5,12-dihydroxyicosa-6,8,10,14-tetraenedioic acid;20-hydroxy-20-oxoleukotriene B4;6,8,10,14-Eicosatetraenedioic acid, 5,12-dihydroxy-, (5S,6Z,8E,10E,12R,14Z)-
Price1 Properties Safety Information Description
1 prices
Selected condition：

Brand

  • Sigma-Aldrich(India)

Package

  • 25μG
  • ManufacturerSigma-Aldrich(India)
  • Product numberC6046
  • Product description20-Carboxy-leukotriene B4 ~1?mg/mL in ethanol, ≥90% (HPLC)
  • Packaging25μG
  • Price₹33290
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) C6046 20-Carboxy-leukotriene B4 ~1?mg/mL in ethanol, ≥90% (HPLC) 25μG ₹33290 2022-06-14 Buy

Properties

Boiling point :588.3±50.0 °C(Predicted)
Density :1.151±0.06 g/cm3(Predicted)
Flash point :14℃
storage temp. :−20°C
solubility :DMF: 50 mg/ml; DMSO: 50 mg/ml; Ethanol: 50 mg/ml; PBS pH 7.2: 1 mg/ml
form :Liquid
pka :4.66±0.10(Predicted)
color :Colorless to light yellow

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H225 Highly Flammable liquid and vapour Flammable liquids Category 2 Danger GHS hazard pictograms P210,P233, P240, P241, P242, P243,P280, P303+ P361+P353, P370+P378,P403+P235, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

20-carboxy LTB4 is a metabolite of LTB4 in human neutrophils. In human leukocytes, LTB4 is inactivated by the enzyme LTB4 20-hydroxylase. The resulting 20-hydroxy LTB4 is further oxidized to 20-carboxy LTB4. LTB4 metabolism in isolated rat hepatocytes also results in production of 20-carboxy LTB4 along with other ω-oxidation products. The biological activity of 20-carboxy LTB4 is only about 2.6% compared to that of LTB4 in causing PMNL degranulation.

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Suppliers and manufacturers

BIOMOL INTERNATIONAL, LP Biomol Feinchemikalien GmbH Interchim S.A. Tebu-bio 3B Scientific Corporation CARBONE SCIENTIFIC CO.,LTD SIGMA-RBI Riedel-de Haen AG Shanghai Hao Zhun Biological Technology Co., Ltd. Resenbio