4-PHENYLAMINO-6,7-DIMETHOXYQUINAZOLINE
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- Product name: 4-PHENYLAMINO-6,7-DIMETHOXYQUINAZOLINE
- CAS: 21561-09-1
- MF: C16H15N3O2
- MW: 281.31
- EINECS:
- MDL Number:MFCD01815294
- Synonyms:WHI-P258;4-Quinazolinamine, 6,7-dimethoxy-N-phenyl-;N-(6,7-DIMETHOXY-4-QUINAZOLINYL)-N-PHENYLAMINE;6,7-dimethoxy-N-phenylquinazolin-4-amine;JAK3 INHIBITOR, NEGATIVE CONTROL;4-PHENYLAMINO-6,7-DIMETHOXYQUINAZOLINE;6,7-DIMETHOXY-N-PHENYL-4-QUINAZOLINAMINE;JAK3 INHIBITOR NEGATIVE CONTROL;WHIP258;WHI P258
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Properties
Boiling point :441.2±40.0 °C(Predicted)
Density :1?+-.0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMF: 25 mg/ml; DMF:PBS(pH 7.2)(1:1): 0.5 mg/ml; DMSO: 15 mg/ml
form :A crystalline solid
pka :6.19±0.70(Predicted)
color :White to off-white
Density :1?+-.0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMF: 25 mg/ml; DMF:PBS(pH 7.2)(1:1): 0.5 mg/ml; DMSO: 15 mg/ml
form :A crystalline solid
pka :6.19±0.70(Predicted)
color :White to off-white
Safety Information
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Description
WHI-P258 is a quinazoline compound that modeling studies suggested would bind to the active site of JAK3 with an estimated Ki value of 72 μM. However, it is inactive at JAK3 (IC50 = >300 μM) and has been used as a negative control for structurally similar compounds that inhibit platelet aggregation and herpes simplex virus 1 (HSV-1) replication.Related product price
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₹6200-28660 - WH-4-023
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₹21460