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1,3-DiMethyl-6-aMino-1H-indazole

1,3-DiMethyl-6-aMino-1H-indazole Structure
  • ₹0
  • Product name: 1,3-DiMethyl-6-aMino-1H-indazole
  • CAS: 221681-92-1
  • MF: C9H11N3
  • MW: 161.2
  • EINECS:
  • MDL Number:MFCD18432764
  • Synonyms:1,3-DiMethyl-6-aMino-1H-i...;1,3-DiMethyl-6-aMino-1H-indazole;1,3-dimethyl-1H-indazol-6-amine;1H-Indazol-6-amine, 1,3-dimethyl-;1,3-Dimethylindazol-6-amine;Pazopanib Impurity 17;1,3-Dimethyl-1H-indazol-6-ylamine
Manufacturer Product number Product description Packaging Price Updated Buy

Properties

Boiling point :335.4±22.0 °C(Predicted)
Density :1.23±0.1 g/cm3(Predicted)
storage temp. :Keep in dark place,Inert atmosphere,Room temperature
pka :3.93±0.50(Predicted)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H320 Causes eye irritation Serious eye damage/eye irritation Category 2B Warning P264, P305+P351+P338,P337+P313
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

1,3-dimethyl-1H-indazol-6-amine is an impurity in the synthesis of Pazopanib (P210925) which is an oral angiogenesis inhibitor targeting VEGFR and PDGFR. It is used as a reagent in the preparation of glycinamide derivatives which are useful in production of drugs for preventing and treating diseases caused by S-adenosyl homocysteine hydrolase.

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