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ChemicalBook > Product Catalogue >Pharmaceutical intermediates >Bulk Drug Intermediates >N-(2-chloropyriMidin-4-yl)-N,2,3-triMethyl-2H-indazol-6-aMine

N-(2-chloropyriMidin-4-yl)-N,2,3-triMethyl-2H-indazol-6-aMine

N-(2-chloropyriMidin-4-yl)-N,2,3-triMethyl-2H-indazol-6-aMine Structure
  • ₹0
  • Product name: N-(2-chloropyriMidin-4-yl)-N,2,3-triMethyl-2H-indazol-6-aMine
  • CAS: 444731-75-3
  • MF: C14H14ClN5
  • MW: 287.75
  • EINECS:810-050-2
  • MDL Number:MFCD12923006
  • Synonyms:N-(2-chloropyriMidin-4-yl)-N,2,3-triMethyl-2H-indazol-6-aMine;N-(2-chloro-4-pyriMidinyl)-N,2,3-triMethyl-2H-indazol-6-aMine;2H-Indazol-6-aMine, N-(2-chloro-4-pyriMidinyl)-N,2,3-triMethyl-;6-[N-(2-chloro-4-pyriMidinyl)MethylaMino]-2,3-diMethyl-2H-indazole, 96%;N-(2-ChloropyriMidin-4-yl)-N-Methyl-2,3-diMethyl-2H-indazol-6-aMine;2,3-dimethyl-N-(2-chloropyrimidin-4-yl)-N-methyl-2H-indazol-6-amine;BNKY007-PZ02;2H-indazole-6-aMine，N-(2-chloro -4-pyrimidinyl)-N,2,3-trimethyl-
Properties Safety Information Description
Manufacturer Product number Product description Packaging Price Updated Buy

Properties

Melting point :167-173℃
Boiling point :524.4±35.0 °C(Predicted)
Density :1.33±0.1 g/cm3(Predicted)
storage temp. :under inert gas (nitrogen or Argon) at 2-8°C
solubility :Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Very Slightly)
pka :2.82±0.30(Predicted)
Stability :Hygroscopic
CAS DataBase Reference :444731-75-3

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405 Store locked up.

Description

N-(2-Chloro-4-pyrimidinyl)-N,2,3-trimethyl-2H-indazol-6-amine is an impurity of Pazopanib (P210925), an oral angiogenesis inhibitor targeting VEGFR and PDGFR.

More related product prices

5-[[4-[(2,3-DiMethyl-2H-indazol-6-yl)aMino]-2-pyriMidinyl]aMino]-2-MethylbenzenesulfonaMide 4(1H)-Pyrimidinone, 2-chloro- (9CI) 1,3-DiMethyl-6-aMino-1H-indazole 2(1H)-Pyrimidinone, 4-chloro- (6CI,9CI) 5-BROMO-3-METHYLINDOLE Pazopanib 2,3-dimethyl-2H-indazol-6-amine hydrochloride Pazopanib-d6 N-(2-chloropyriMidin-4-yl)-2,3-diMethyl-2H- indazol-6-aMine (4R,12aS)-7-Methoxy-4-Methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-[1,3]oxazino[3,2-d]pyrido[1,2-a]pyrazine-9-carboxylic acid (6a,11b,16a,17a)-6,9-Difluoro-11,17-dihydroxy-16-methyl-3-oxoandrosta-1,4-diene-17-carboxylic acid 4-Acetoxy-3-acetoxymethylacetophenone 2-Methyl-5-nitrobenzenesulfonamide 3-AMINO-4-METHYLBENZENESULFONAMIDE 2,3-DIMETHYL-6-NITRO-2H-INDAZOLE

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Suppliers and manufacturers

Kalam Sai Life Sciences Pvt Ltd Litha Life Sciences Pvt Limited Lakshana Biotechnologies Private Limited Vidgas science and technologies Pvt Ltd ANAXLABORATORIES PRIVATE LIMITED Stereokem Pvt Ltd Synergene Active Ingredients Pvt. Ltd. ALS INDIA LIFE SCIENCES Kekule Pharma Limited Raising Sun Pharma