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(S)-2,2-Dimethyl-1,3-dioxolane-4-methanol p-toluenesulfonate

(S)-2,2-Dimethyl-1,3-dioxolane-4-methanol p-toluenesulfonate Structure
  • ₹7600 - ₹40539.63
  • Product name: (S)-2,2-Dimethyl-1,3-dioxolane-4-methanol p-toluenesulfonate
  • CAS: 23735-43-5
  • MF: C13H18O5S
  • MW: 286.34
  • EINECS:
  • MDL Number:MFCD00063234
  • Synonyms:(S)-O-ISOPROPYLIDENE GLYCEROL TOSYLATE;(S)-(+)-2,2-DIMETHYL-4-(HYDROXYMETHYL)-1,3-DIOXOLANE-P-TOLUENESULFONATE;(S)-2,2-DIMETHYL-4-(HYDROXYMETHYL)-1,3-DIOXOLANE-P-TOLUENESULFONATE;(S)-(+)-2,2-DIMETHYL-4-(HYDROXYMETHYL)-1,3-DIOXOLANE-P-TOLUENSULFONATE;(S)-(+)-2,2-DIMETHYL-1,3-DIOXOLAN-4-YLMETHYL P-TOLUENESULFONATE;(S)-2,2-DIMETHYL-1,3-DIOXOLANE-4-METHANOL-4-METHYLBENZENESULFONATE;2,3-ISOPROPYLIDENE-SN-GLYCEROL 1-TOSYLATE;2,2-DIMETHYL-4(S)-4-(P-TOLYLSULFONYL)METHYL-1,3-DIOXALANE
4 prices
Selected condition:

Brand

  • TCI Chemicals (India)
  • Sigma-Aldrich(India)

Package

  • 1G
  • 5G
  • ManufacturerTCI Chemicals (India)
  • Product numberD2550
  • Product description(S)-(+)-2,2-Dimethyl-1,3-dioxolan-4-ylmethyl p-Toluenesulfonate min. 98.0 %
  • Packaging1G
  • Price₹7600
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberD2550
  • Product description(S)-(+)-2,2-Dimethyl-1,3-dioxolan-4-ylmethyl p-Toluenesulfonate min. 98.0 %
  • Packaging5G
  • Price₹29500
  • Updated2022-05-26
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number337420
  • Product description(S)-(+)-2,2-Dimethyl-1,3-dioxolan-4-ylmethyl p-toluenesulfonate 97%
  • Packaging1G
  • Price₹11506.98
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number337420
  • Product description(S)-(+)-2,2-Dimethyl-1,3-dioxolan-4-ylmethyl p-toluenesulfonate 97%
  • Packaging5G
  • Price₹40539.63
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
TCI Chemicals (India) D2550 (S)-(+)-2,2-Dimethyl-1,3-dioxolan-4-ylmethyl p-Toluenesulfonate min. 98.0 % 1G ₹7600 2022-05-26 Buy
TCI Chemicals (India) D2550 (S)-(+)-2,2-Dimethyl-1,3-dioxolan-4-ylmethyl p-Toluenesulfonate min. 98.0 % 5G ₹29500 2022-05-26 Buy
Sigma-Aldrich(India) 337420 (S)-(+)-2,2-Dimethyl-1,3-dioxolan-4-ylmethyl p-toluenesulfonate 97% 1G ₹11506.98 2022-06-14 Buy
Sigma-Aldrich(India) 337420 (S)-(+)-2,2-Dimethyl-1,3-dioxolan-4-ylmethyl p-toluenesulfonate 97% 5G ₹40539.63 2022-06-14 Buy

Properties

Melting point :29-31 °C
alpha :4.2 º (c=10, abs.alcohol)
Boiling point :398.71°C (rough estimate)
Density :1.208 g/mL at 25 °C(lit.)
refractive index :n20/D 1.506(lit.)
Flash point :>230 °F
storage temp. :Inert atmosphere,2-8°C
form :powder to lump to clear liquid
color :White or Colorless to Light yellow
optical activity :[α]26/D +7.5°, c = 2% in DMF
BRN :89799
CAS DataBase Reference :23735-43-5(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

(S)-(+)-2,2-Dimethyl-1,3-dioxolan-4-ylmethyl p-Toluenesulfonate has been used as a reactant for the synthesis of 16-(3-trifluoromethyl)phenoxy PGF2α analog travoprost (T715600) which has potent topical ocular activity. (S)-(+)-2,2-Dimethyl-1,3-dioxolan-4-ylmethyl p-Toluenesulfonate has also been used for the preparation of p38 mitogen activated protein (MAP) kinase inhibitors.

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