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5-Methoxyindole-3-acetonitrile

5-Methoxyindole-3-acetonitrile Structure
  • ₹0
  • Product name: 5-Methoxyindole-3-acetonitrile
  • CAS: 2436-17-1
  • MF: C11H10N2O
  • MW: 186.21
  • EINECS:
  • MDL Number:MFCD02094163
  • Synonyms:5-METHOXY-3-INDOLYLACETONITRILE;5-METHOXYINDOLE-3-ACETONITRILE;(5-METHOXY-1H-INDOL-3-YL)ACETONITRILE;2-(5-Methoxy-1H-indol-3-yl)acetonitrile;5-METHOXY-3-INDOLYLACETONITRILE 97%;5-Methoxy indol - 3 -yl Acetonitrile;3-(Cyanomethyl)-5-methoxy-1H-indole;3-(Cyanomethyl)-5-methoxyindole
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Properties

Melting point :65-69 °C (lit.)
Boiling point :175-177 °C(Press: 0.01 Torr)
Density :1.224±0.06 g/cm3(Predicted)
storage temp. :-20°C Freezer
solubility :Chloroform (Slightly), Methanol (Slightly)
form :Solid
pka :16.02±0.30(Predicted)
color :Very Dark Brown
CAS DataBase Reference :2436-17-1(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
Precautionary statements:
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

5-Methoxyindole-3-acetonitrile is a versatile reactant used in the preparation of indole-N-acetic acid derivatives as aldose reductase inhibitors for diabetic complications treatment. It is also used in the synthesis of carboline analogs as potent MAPKAP-K2 inhibitors.

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