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ChemicalBook > Product Catalogue >Biochemical Engineering >Plant extracts >BIS(4-HYDROXYCINNAMOYL)METHANE

BIS(4-HYDROXYCINNAMOYL)METHANE

BIS(4-HYDROXYCINNAMOYL)METHANE Structure
  • ₹5000 - ₹10600
  • Product name: BIS(4-HYDROXYCINNAMOYL)METHANE
  • CAS: 24939-16-0
  • MF: C19H16O4
  • MW: 308.33
  • EINECS:607-464-9
  • MDL Number:MFCD03419284
  • Synonyms:BIS-DESMETHOXYCURCUMIN;BIS(4-HYDROXYCINNAMOYL)METHANE;DEMETHOXYCURCUMIN, BIS-;CURCUMIN 3;(1E,6E)-1,7-bis(4-hydroxyphenyl)hepta-1,6-diene-3,5-dione;BIS-(PARA-HYDROXYCINNAMOYL)METHANE;CURCUMINIII;1,7-Bis(4-hydroxyphenyl)-1,6-heptadiene-3,5-dione
2 prices
Selected condition:

Brand

  • TCI Chemicals (India)

Package

  • 5G
  • 25G
  • ManufacturerTCI Chemicals (India)
  • Product numberB3347
  • Product descriptionBisdemethoxycurcumin
  • Packaging5G
  • Price₹5000
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberB3347
  • Product descriptionBisdemethoxycurcumin
  • Packaging25G
  • Price₹10600
  • Updated2022-05-26
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
TCI Chemicals (India) B3347 Bisdemethoxycurcumin 5G ₹5000 2022-05-26 Buy
TCI Chemicals (India) B3347 Bisdemethoxycurcumin 25G ₹10600 2022-05-26 Buy

Properties

Melting point :91-93℃
Boiling point :551.3±45.0 °C(Predicted)
Density :1.285
storage temp. :2-8°C
solubility :DMSO: ≥20mg/mL
pka :8.67±0.46(Predicted)
form :Solid
color :Light yellow to Brown
Stability :Light Sensitive
InChIKey :PREBVFJICNPEKM-YDWXAUTNSA-N
LogP :3.155 (est)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection.

Description

Bisdemethoxycurcumin (BDMC) is a natural demethoxy derivative of curcumin. It is a potent activator of macrophage phagocytosis, interacting with 1α,25-dihydroxyvitamin D3 to stimulate amyloid-β clearance by macrophages (optimal stimulation at 100 nM BDMC). More stable than curcumin in physiological media, BDMC suppresses proliferation in cancer cells. It down-regulates the transcriptional coactivator p300, suppressing the Wnt/β-catenin pathway, and inhibits LPS induction of iNOS expression.

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