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ChemicalBook > Product Catalogue >Pharmaceutical intermediates >Bulk Drug Intermediates >5-Chloromethyl-2H-1,2,4-triazolin-3-one

5-Chloromethyl-2H-1,2,4-triazolin-3-one

5-Chloromethyl-2H-1,2,4-triazolin-3-one Structure
  • ₹7600 - ₹14800
  • Product name: 5-Chloromethyl-2H-1,2,4-triazolin-3-one
  • CAS: 252742-72-6
  • MF: C3H4ClN3O
  • MW: 133.54
  • EINECS:607-678-2
  • MDL Number:MFCD07776630
  • Synonyms:5-CHLOROMETHYL-2,4-DIHYDRO-[1,2,4]TRIAZOL-3-ONE;3-(chloroMethyl)-4,5-dihydro-1H-1,2,4-triazol-5-one;5-(CHLOORMETHYL)-1,2-DIHYDRO-3H-1,2,4-TRIAZOOL-3-ON;5-ChloroMethyl-2H-1,2,4-triazolin-3-one;3-Chloromethyl-1,2,4-triazolin-5-one,Aprepitant intermediate;3-Chloromethyl-1,2,4-triazolin-5-one 5-Chloromethyl-2,4-dihydro-[1,2,4]triazol-3-one;Aprepitant int-2 3-chloromethyl-1,2,4-triazolin-5-one;5-(chloromethyl)-1,2-dihydro-1,2,4-triazol-3-one
2 prices
Selected condition:

Brand

  • TCI Chemicals (India)

Package

  • 1G
  • 5G
  • ManufacturerTCI Chemicals (India)
  • Product numberC3094
  • Product description3-(Chloromethyl)-1,2,4-triazolin-5-one
  • Packaging1G
  • Price₹7600
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberC3094
  • Product description3-(Chloromethyl)-1,2,4-triazolin-5-one
  • Packaging5G
  • Price₹14800
  • Updated2022-05-26
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
TCI Chemicals (India) C3094 3-(Chloromethyl)-1,2,4-triazolin-5-one 1G ₹7600 2022-05-26 Buy
TCI Chemicals (India) C3094 3-(Chloromethyl)-1,2,4-triazolin-5-one 5G ₹14800 2022-05-26 Buy

Properties

Melting point :199°C(lit.)
Density :1.83±0.1 g/cm3(Predicted)
storage temp. :Keep in dark place,Sealed in dry,Room Temperature
solubility :soluble in Methanol
form :powder to crystal
pka :7.46±0.20(Predicted)
color :White to Almost white
CAS DataBase Reference :252742-72-6

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H290 May be corrosive to metals Corrosive to Metals Category 1 Warning GHS hazard pictograms P234, P390, P404
H314 Causes severe skin burns and eye damage Skin corrosion/irritation Category 1A, B, C Danger GHS hazard pictograms P260,P264, P280, P301+P330+ P331,P303+P361+P353, P363, P304+P340,P310, P321, P305+ P351+P338, P405,P501
Precautionary statements:
P234 Keep only in original container.
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P330+P331 IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.
P303+P361+P353 IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P363 Wash contaminated clothing before reuse.
P390 Absorb spillage to prevent material damage.
P405 Store locked up.
P406 Store in corrosive resistant/… container with a resistant inner liner.
P501 Dispose of contents/container to..…

Description

5-Chloromethyl-2H-1,2,4-triazolin-3-one is an intermediate used in the synthesis of Aprepitant (A729800) and Fosaprepitant, used as antiemetic drugs.

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