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1-(2-TRIFLUOROMETHYLPHENYL)IMIDAZOLE

1-(2-TRIFLUOROMETHYLPHENYL)IMIDAZOLE Structure
  • ₹6000 - ₹21900
  • Product name: 1-(2-TRIFLUOROMETHYLPHENYL)IMIDAZOLE
  • CAS: 25371-96-4
  • MF: C10H7F3N2
  • MW: 212.17
  • EINECS:636-734-9
  • MDL Number:MFCD00041206
  • Synonyms:I-(2-TRIFLUOROMETHYLPHENYL)IMIDAZOLE;1-(ALPHA,ALPHA,ALPHA-TRIFLUORO-O-TOLYL)-IMIDAZOLE;1-(2-TRIFLUOROMETHYLPHENYL)IMIDAZOLE;1-[2-(TRIFLUOROMETHYL)PHENYL]-1H-IMIDAZOLE;TRIM;1-[2-(Trifluoromethyl)phenyl]-1H-imidazole 98%;1-[2-(Trifluoromethyl)phenyl]-1H-imidazole98%;1-(2-Trifluoromethylphenyl)imidazole, 98+%
3 prices
Selected condition:

Brand

  • TCI Chemicals (India)
  • Sigma-Aldrich(India)

Package

  • 100MG
  • 200MG
  • 1G
  • ManufacturerTCI Chemicals (India)
  • Product numberT2982
  • Product description1-[2-(Trifluoromethyl)phenyl]imidazole min. 98.0 %
  • Packaging200MG
  • Price₹6000
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberT2982
  • Product description1-[2-(Trifluoromethyl)phenyl]imidazole min. 98.0 %
  • Packaging1G
  • Price₹21900
  • Updated2022-05-26
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberT7313
  • Product description1-[2-(Trifluoromethyl)phenyl]imidazole
  • Packaging100MG
  • Price₹14029.2
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
TCI Chemicals (India) T2982 1-[2-(Trifluoromethyl)phenyl]imidazole min. 98.0 % 200MG ₹6000 2022-05-26 Buy
TCI Chemicals (India) T2982 1-[2-(Trifluoromethyl)phenyl]imidazole min. 98.0 % 1G ₹21900 2022-05-26 Buy
Sigma-Aldrich(India) T7313 1-[2-(Trifluoromethyl)phenyl]imidazole 100MG ₹14029.2 2022-06-14 Buy

Properties

Melting point :43 °C
Boiling point :75°C 0,02mm
Density :1.3253 (estimate)
Flash point :75°C/0.025mm
storage temp. :2-8°C
solubility :Soluble in DMSO (up to 10 mg/ml) or in Ethanol (up to 20 mg/ml).
form :White solid.
pka :4.96±0.10(Predicted)
color :White
Sensitive :Light Sensitive
BRN :3955637
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
CAS DataBase Reference :25371-96-4(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

TRIM is an inhibitor of nNOS and iNOS. It exhibits IC50 values of 28.2 μM, 27.0 μM, and 1.06 mM for the inhibition of nNOS (mouse), iNOS (rat), and eNOS (bovine), respectively. TRIM inhibits mouse nNOS with Ki values of 47.3 and 462 μM in the absence and presence of BH4, respectively, suggesting TRIM interferes with both arginine and tetrahydrobiopterin binding.

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